Molluscum‐contagiosum‐Virus in einer Epidermalzyste

Müller, Cornelia; Laue, Michael; Kremer, K; Becker, S; Vogt, Thomas; Smola, Sigrun

doi:10.1111/ddg.13633_g

Cited by 4 publications

(5 citation statements)

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“…Figure 1: Molluscum contagiosum demonstrating a centric, waxy core pervaded with virions confined to superficial stratified squamous epithelial layer [1].…”

Section: Editorialmentioning

confidence: 99%

“…Molluscum contagiosum or 'water warts' emerges as an extremely contagious, cutaneous viral infection engendered by molluscum contagiosum virus of poxvirus family. Molluscum contagiosum virus is confined to superficial cutaneous layers wherein centroidal, waxy core is permeated by the virus [1,2]. Onset of lesions occurs in around seven weeks following viral exposure.…”

Section: Editorialmentioning

confidence: 99%

“…Mean duration of an outbreak of lesions appears at 6 months to five years wherein immunosuppressed individuals demonstrate a prolonged duration [1,2]. Molluscum contagiosum virus disseminates through direct or sexual contact, with contact sports, contact with infected fomites, autoinoculation with scratching or picking the lesions or sharing of contaminated objects as towels.…”

Section: Editorialmentioning

confidence: 99%

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The Flourishing Miasma-Molluscum Contagiosum

Bajaj¹

2022

BJSTR

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“…Figure 1: Molluscum contagiosum demonstrating a centric, waxy core pervaded with virions confined to superficial stratified squamous epithelial layer [1].…”

Section: Editorialmentioning

confidence: 99%

Section: Editorialmentioning

confidence: 99%

Section: Editorialmentioning

confidence: 99%

See 1 more Smart Citation

The Flourishing Miasma-Molluscum Contagiosum

Bajaj¹

2022

BJSTR

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“…Transmission of MC is by direct contact with infected skin (contact can be sexual, non-sexual or autoinoculation) or by contaminated fomites like towels or sponges, etc. 3,4 Presentation of the lesions of MC can be single, multiple, or clustered, with sometimes appearance of an erythematous halo. 5 The diagnosis of Molluscum contagiosum is clinical, primarily based on the distinguishing traits of the lesions.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of 5% Potassium Hydroxide Versus 10% Potassium Hydroxide Solution for the Treatment of Molluscum Contagiosum at a Tertiary Care Hospital

Baloch

Ahmed

Bari

et al. 2021

PAFMJ

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Objective: To compare the efficacy of 5% potassium hydroxide (KOH) and 10% potassium hydroxide (KOH) solution for the treatment of molluscum contagiosum at a tertiary care Hospital. Study Design: Quasi-experimental study. Place and Duration of Study: Dermatology Department, Tertiary Care Hospital Karachi, from Oct 2019 to Apr 2021. Methodology: Sixty patients with molluscum contagiosum who fulfilled the inclusion and exclusion criteria were enrolled in the outpatient department of tertiary care hospital in Karachi. Patients were divided into two groups, A (5% KOH) and B (10% KOH) of 30 patients each. Potassium Hydroxide (KOH) solution was applied at home using the cotton-tipped applicator twice daily. Follow-up of patients was done at 2-weekly intervals for 12 weeks. Efficacy was measured based on the resolution of lesions or improvement from baseline. Results: Complete response occurred in 23 (76.7%) cases in 10% KOH Group while 6 (20%) in 5% KOH Group, Partial response occurred in 6 (20%) in 10% KOH group while 15 (50%) in 5% KOH group, No response occurred in 1 (3.33%) in 10% KOH group and 9 (30%) in 5% KOH group (p<0.001). Conclusion: 10% Potassium Hydroxide (KOH) is an efficient modality for the treatment of molluscum contagiosum compared to 5% Potassium Hydroxide (KOH).

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“…Molluscum contagiosum (MC) is a common, benign viral skin infection in children, characterized by a dome-shaped, round, and pinkish papula, caused by a Pox virus family. [1][2][3] This skin disease is usually self-limiting, hence awaiting spontaneous resolution should be considered. Current treatment options include physical elimination through curettage or cryotherapy, topical medications with salicylic acid (SAL), lactic acid (LAC), tretinoin, cantharidin, podophyllotoxin, imiquimod, hydrogen peroxide or potassium hydroxide (KOH), and systemic treatment with cimetidine.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Side Effects of Topical Applications of Two Different Solutions in the Treatment of Molluscum Contagiosum in a City in Africa: An Open, Randomized, Comparative Clinical Trial

Öztürk

2019

J Pediatr Infect Dis

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Molluscum contagiosum (MC) is one of the most common viral infections in African children. However, there is no work investigating the treatment of MC in dark skinned children in Africa. In this study, we aimed to compare efficacy and side effects of topical application of 10% potassium hydroxide (KOH) and 16.7% salicylic acid (SAL) and lactic acid (LAC) combination in the treatment of MC in Sudan, Africa. This is a prospective, randomized, and comparative study. The inclusion criterion was the presence of at least 10 lesions. The exclusion criteria were the use of any topical MC treatment during the last 2 weeks, immunosuppression, periorbital and perioral involvement, the history of hypersensitivity to any kind of keratolytics, and the presence of concomitant bacterial skin infections. The main efficacy outcome was the complete remission or partial remission. Three visits were performed: baseline visit (diagnosis, randomization, and therapy initiation), visit 1 for follow-up (at 15–30 days after initiation of therapy and for study end), and visit 2 for postclearing assessment (at 60th day after the initiation of therapy). Chi-squared (χ2) test was used. All patients (n = 101) participating completed the 60 days of follow-up period. Post 60 days of treatment, the rates of complete resolution in 55 patients treated with 10% KOH solution and 47 patients treated with 16.7% SAL + LAC combination solution were 87.0 and 85.1% (p > 0.05), respectively. The rates of partial resolution in the group treated with KOH solution and in patients treated with SAL + LAC combination solution were 12.9% and 14.8% (p > 0.05), respectively. Major side effects in KOH group were burning sensation or stinging during application (48.1%, p = 0.0009) and hypopigmentation (38.8%, p = 0.007) while it was desquamation (23.4%, p > 0.05) in the SAL + LAC combination group. Results indicate both 10% KOH solution and SAL + LAC combination solution showed good efficacy in the treatment of MC in African children. Neither 10% KOH nor the SAL + LAC combination solution was found superior to other in the treatment, while the latter was noted to have fewer side effects. Permanent hypopigmentation is an important and undesired side effect of 10% KOH treatment.

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Molluscum‐contagiosum‐Virus in einer Epidermalzyste

Cited by 4 publications

References 0 publications

The Flourishing Miasma-Molluscum Contagiosum

The Flourishing Miasma-Molluscum Contagiosum

Efficacy of 5% Potassium Hydroxide Versus 10% Potassium Hydroxide Solution for the Treatment of Molluscum Contagiosum at a Tertiary Care Hospital

Efficacy and Side Effects of Topical Applications of Two Different Solutions in the Treatment of Molluscum Contagiosum in a City in Africa: An Open, Randomized, Comparative Clinical Trial

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