Molybdenum and Tungsten Carbonyl Complexes With N<sub>2</sub> Schiff Base Donors: Syntheses, Spectral, Electrochemical, Thermal, Catalytic Epoxidation, and Biological Activity Studies

Mohamed, Rania G.; Elantabli, Fatma M.; Helal, N.H.; El‐Medani, Samir M.

doi:10.1080/15533174.2013.872138

Cited by 17 publications

(2 citation statements)

References 58 publications

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“…The characteristic vibration bands of HL ligand show the proper shifts on complexation indicating the complex formation ( Table 3). and 1211-1228 cm -1 , respectively, with the proper shifts with respect to the corresponding values in the ligand [35,36]. These results indicated the coordination of nitrogen of the thiazole ring, azomethine nitrogen and hydroxyl oxygen of the ligand to the metal ions; Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) [37].…”

Section: Ir Spectramentioning

confidence: 67%

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

El-Medanib

Aaziza

Mohamed

et al. 2018

Journal of Scientific Research in Science

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Thermal reaction of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Ru(III) metal ions with a tridentate Schiff-base ligand(HL) derived from the condensation of 2-aminothiazole and 2hydroxy-1-naphthaldehyde resulted in the formation of a series of six new metal complexes: [Co(HL) 2 Cl 2 ]; 1,[Ni(L)(CH 3 COO)(H 2 O)]; 2,[Cu(L) 2 ]; 3, [Zn(L) 2 ]; 4, [Cd(L)(CH 3 COO) (H 2 O)]H 2 O; 5, [Ru(L) 2 (H 2 O) 2 ]Cl; 6. The ligand and its complexes were characterized by means of elemental and thermal analyses along with molar conductance and magnetic moment measurements as well as different spectroscopic techniques. The ESR spectrum of Cu(II) complex indicated elongated and covalent character of octahedral environment.

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Section: Ir Spectramentioning

confidence: 67%

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

El-Medanib

Aaziza

Mohamed

et al. 2018

Journal of Scientific Research in Science

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“…[71] Chelation process can significantly decrease the metal ions' polarity as a result of the partial sharing of the positive charge with the π-electron delocalization of the chelation ring and the electron donor groups, which increases the metal complex penetration through the lipid membranes, progressively impacting different cell processes, activating many enzymes, and changing metabolic processes. [5,[71][72][73] In addition, transition metal complexes possess more enhanced biophysical and biological properties such as stability, metabolism, binding, and oral drug delivery properties than their parent ligands. [74] Moreover, the variety of functional groups in the formed heteroleptic complexes enhances the interactions of the metal ions with cell components.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Synthesis, structural characterization, density functional theory calculations, and antimicrobial, anticancer, and antimetastatic properties of nanosized heteroleptic complexes of cocaine/TMEDA with d‐block metal ions

Abdallah

Zaki

Mahmoud

et al. 2021

Applied Organom Chemis

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In the field of transition metal chemistry, the development of transition metal‐based drugs for the treatment of diseases such as cancer or microbial infections with minimization of adverse effects and drug resistance constitutes an active area of research. Herein, eight novel nanosized heteroleptic complexes of cocaine/TMEDA with the formula [M(COC)(TMEDA)Cly(OH2)z]nCl·xH2O (M = Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II); COC = cocaine; TMEDA = N,N,N′,N′‐tetramethylethylenediamine, y = 1–2; z = 0–1; n = 0–1; and x = 0–2) were synthesized and structurally characterized via elemental analysis, molar conductivity, mass spectrometry, and spectroscopic and microscopic techniques. The thermal properties and kinetic thermodynamic parameters of the synthesized complexes were also studied. The geometry and electronic structures were investigated via density functional theory (DFT) calculations. The antiproliferative activity of the complexes on HepG‐2 and MCF‐7 cancer cell lines was quantified via MTT assay. The Fe(III) and Cd(II) complexes exhibited promising cytotoxic activities against the HepG‐2 and MCF‐7 cancer cell lines, respectively, with minimum effect on HFB4 human normal cells. Further molecular mechanistic studies were performed on the Cd(II) complex to inspect its influence on different cancer pathophysiology‐related processes in the MCF‐7 cell line including metastasis, apoptosis, and cellular oxidative stress and on the cellular levels of the human tumor suppressor nuclear proteins p21 and p27. The results revealed that the Cd(II) complex is a promising anticancer agent that acts through several molecular mechanisms with minimum effect on the normal cells and with additional antimetastatic properties. Furthermore, the antibacterial and antifungal activities of the prepared complexes were investigated.

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Easily attainable new approach to mass yield ferrocenyl Schiff base and different metal complexes of ferrocenyl Schiff base through convenient ultrasonication‐solvothermal method

Elseman

Shalan

Rashad

et al. 2016

J of Physical Organic Chem

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A new alternative approach with crucial mass yield and high reaction rates is proposed for the synthesis of ferrocenyl Schiff bases using an ultrasonicationsolvothermal method. Equimolar condensation of ferrocenecarboxaldehyde and 2-aminophenol interact with each other, giving 1-(1-[2-hydroxyphenyl-2-imino] methyl)-ferrocene (FcOH). Furthermore, this ligand forms 1:1 complexes with cobalt(II), nickel(II), copper(II), and palladium(II) ions. From the different spectral data, it is found that metal ions coordinate with ligands through the azomethine group and the deprotonated oxygen of the phenol groups. Moreover, FcOH and their complexes were characterized by elemental analysis, Fourier transform infrared, 1 H nuclear magnetic resonance, and UV-visible spectrophotometry. The spectral data of FcOH and its metal complexes were discussed in connection with the structural changes due to complexation. Meanwhile, the information about geometric structures can be concluded from the electronic spectra and the magnetic moments. Plainly, electron spin resonance spectra of the Cu(II) complex revealed d x2−y2 as a ground state, suggesting a square planar geometry around the Cu(II) center. The direct optical band gap energy E g values of cobalt, nickel, copper, and palladium complexes of FcOH are found to be 3.7, 3.9, 4.6, and 3.65 eV, respectively. 1-(1-[2-Hydroxyphenyl-2-imino]methyl)-ferrocene and its metal complexes were screened for antibacterial activity. The results depict that the metal complexes were found to be more strongly antibacterial than the guardian Schiff base ligand (FcOH) against one or more bacterial species. The minimum inhibitory concentrations of antimicrobial properties of the purified compound were determined using the broth microdilution method.

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Molybdenum and Tungsten Carbonyl Complexes With N₂ Schiff Base Donors: Syntheses, Spectral, Electrochemical, Thermal, Catalytic Epoxidation, and Biological Activity Studies

Cited by 17 publications

References 58 publications

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

Synthesis, structural characterization, density functional theory calculations, and antimicrobial, anticancer, and antimetastatic properties of nanosized heteroleptic complexes of cocaine/TMEDA with d‐block metal ions

Easily attainable new approach to mass yield ferrocenyl Schiff base and different metal complexes of ferrocenyl Schiff base through convenient ultrasonication‐solvothermal method

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Molybdenum and Tungsten Carbonyl Complexes With N2 Schiff Base Donors: Syntheses, Spectral, Electrochemical, Thermal, Catalytic Epoxidation, and Biological Activity Studies

Cited by 17 publications

References 58 publications

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

Synthesis and characterization of Zn(II), Cu(II), Co(II), Ni(II), Cd(II) and Ru(III) ions with a tridentate NNO thiazole derived Schiff base

Synthesis, structural characterization, density functional theory calculations, and antimicrobial, anticancer, and antimetastatic properties of nanosized heteroleptic complexes of cocaine/TMEDA with d‐block metal ions

Easily attainable new approach to mass yield ferrocenyl Schiff base and different metal complexes of ferrocenyl Schiff base through convenient ultrasonication‐solvothermal method

Contact Info

Product

Resources

About

Molybdenum and Tungsten Carbonyl Complexes With N₂ Schiff Base Donors: Syntheses, Spectral, Electrochemical, Thermal, Catalytic Epoxidation, and Biological Activity Studies