To improve the seismic performance of Chinese traditional wood-structure houses, this paper proposes to strengthen their mortise and tenon joints by applying an innovative metal damper. According to the dimensions of the “Yikeyin” wood-structure houses in the Tonghai area of Yunnan Province, two groups of six samples of three types of mortise and tenon joints were manufactured, in which one group was mounted with dampers made of Q235 steels. Subsequently, a low-cycle repeated loading test was conducted to examine the overall behavior of these joints. Various characteristics of seismic performance indexes, such as the moment–rotation hysteresis curve, skeleton curve, stiffness degradation, energy dissipation capacity, residual amount of tenon and the removal before and after reinforcements of straight, penetrated and dovetail tenon joints were analyzed. The test results show that these tenons exhibit good deformation capacity, their hysteresis curves became fuller and their “pinch” effects were significantly reduced, all after their joints became strengthened, indicating that their joint slips were reduced during the loading processes and their residual amounts of tenon removals were under effective control. Compared with the blank group, the joint stiffness was substantially improved, and the increase in the reverse stiffness turned greater than that of the positive stiffness at each stage of loading, while the degradation curve of the whole joint stiffness became steeper. After mounting the dampers, the bearing capacity and energy dissipation of the joints were significantly improved, the equivalent viscous damping coefficients of the straight and penetrated tenon joints were increased, but that of the dovetail joint was slightly reduced. These study results can provide a reference for the reinforcement and protection of traditional wood-structure houses.