Mometasone furoate intranasal spray is effective in reducing symptoms and adenoid size in children and adolescents with adenoid hypertrophy

Ghafar, Muhammad Hazim Abdul; Mohamed, Hazama; Mohammad, Nik Mohd Yunus; Mohammad, Wan Mohd Zahiruddin Wan; Madiadipoera, Teti; Wang, De Yun; Abdullah, Baharudin

doi:10.1016/j.otorri.2019.04.004

Cited by 4 publications

(2 citation statements)

References 25 publications

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“…MF intranasal spray is endorsed as a treatment option before adenoidectomy as the evidence suggests this as an effective treatment in improving AH symptoms as well as reducing the adenoid size. Ghafar [50] conducted a study to evaluate the effect of MF intranasal spray in children and adolescents with AH. The authors noted significant improvements in nasal obstruction, rhinorrhoea, cough, and snoring in patients after 12 weeks treatment with MF intranasal spray (p < 0.001).…”

Section: Treatment Interventionsmentioning

confidence: 99%

Causes and treatments of nasal obstruction in children and adolescents: a systematic literature review

Javed¹,

Tanveer²

2022

Egypt J Otolaryngol

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Objective To identify the causes and treatments of nasal obstruction in the paediatric population. Methods A systematic search of Medline and Embase was conducted to identify the relevant articles. A detailed inclusion and exclusion criterion was developed and implemented to screen the abstracts. Full texts of the selected studies were then assessed to establish their inclusion or exclusion in our review. All relevant data were extracted, and the results were summarised narratively. Results Fifty-nine studies met out inclusion-exclusion criteria and were included in this systematic review. All of these primary research studies were categorised into causes and treatments. Cleft lip and palate was the most reported cause of nasal obstruction among congenital causes. However, among the acquired causes, allergic rhinitis was the most reported. Twenty-one of 39 studies described treatments for allergic rhinitis, including perennial rhinitis, 9 for adenoid hypertrophy, 2 for the common cold, 5 for septal deviation, and 2 for chronic rhinosinusitis. Conclusion This systematic review provides good evidence regarding the causes and treatments of nasal obstruction. Allergic rhinitis is the most common cause of acquired nasal obstruction, and cetirizine, fexofenadine, fluticasone furoate nasal spray, and mometasone furoate monohydrate nasal are the commonly used treatments to alleviate the symptoms.

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Section: Treatment Interventionsmentioning

confidence: 99%

Causes and treatments of nasal obstruction in children and adolescents: a systematic literature review

Javed¹,

Tanveer²

2022

Egypt J Otolaryngol

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show abstract

“…Mometasone furoate (MF) is a synthetic glucocorticoid that has a high-potency inhibitory effect on inflammatory reactions. It has been reported that MF is very effective in reducing symptoms in chronic rhinosinusitis, persistent asthma and adenoid hypertrophy [11] , [12] , [13] . Although MF has been proven to have the effect of inhibiting the growth of acute lymphoblastic leukemia (ALL 2 ) cells in childhood [14] , the role of MF in osteosarcoma cells is still unknown.…”

Section: Introductionmentioning

confidence: 99%

Mometasone furoate inhibits tumor progression and promotes apoptosis through activation of the AMPK/mTOR signaling pathway in osteosarcoma

Li,

Fei,

Pan

et al. 2024

Journal of Bone Oncology

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Medical treatment does not reduce surgery rates in children with adenoid hypertrophy

Tamir,

Schwarz,

Hazan

et al. 2024

International Journal of Pediatric Otorhinolaryngology

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Mometasone furoate intranasal spray is effective in reducing symptoms and adenoid size in children and adolescents with adenoid hypertrophy

Cited by 4 publications

References 25 publications

Causes and treatments of nasal obstruction in children and adolescents: a systematic literature review

Causes and treatments of nasal obstruction in children and adolescents: a systematic literature review

Mometasone furoate inhibits tumor progression and promotes apoptosis through activation of the AMPK/mTOR signaling pathway in osteosarcoma

Medical treatment does not reduce surgery rates in children with adenoid hypertrophy

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