Mometasone Furoate Nasal Spray Relieves the Ocular Symptoms of Seasonal Allergic Rhinoconjunctivitis

Igarashi, Tsutomu; Nakazato, Yuri; Kunishige, Tomoyuki; Fujita, Miho; Yamada, Yumi; Fujimoto, Chiaki; Okubo, Kimihiro; Takahashi, Hiroshi

doi:10.1272/jnms.79.182

Cited by 8 publications

(10 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… 367 368 Similarly, INSs tend to decrease the SP concentration in tears of patients with seasonal AR, which is correlated with the severity of ocular and nasal symptoms. 369 The efficacy of INS appears after 3–5 hours of dosing, but maximum efficacy may develop over a period of up to 2 weeks.…”

Section: Treatmentmentioning

confidence: 99%

Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Cheng

Chen

et al. 2018

Allergy Asthma Immunol Res

261

198

View full text Add to dashboard Cite

Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries and currently affects up to 40% of the population worldwide. Likewise, a rising trend of AR has also been observed over the last 2–3 decades in developing countries including China, with the prevalence of AR varying widely in these countries. A survey of self-reported AR over a 6-year period in the general Chinese adult population reported that the standardized prevalence of adult AR increased from 11.1% in 2005 to 17.6% in 2011. An increasing number of original articles and imporclinical trials on the epidemiology, pathophysiologic mechanisms, diagnosis, management and comorbidities of AR in Chinese subjects have been published in international peer-reviewed journals over the past 2 decades, and substantially added to our understanding of this disease as a global problem. Although guidelines for the diagnosis and treatment of AR in Chinese subjects have also been published, they have not been translated into English and therefore not generally accessible for reference to non-Chinese speaking international medical communities. Moreover, methods for the diagnosis and treatment of AR in China have not been standardized entirely and some patients are still treated according to regional preferences. Thus, the present guidelines have been developed by the Chinese Society of Allergy to be accessible to both national and international medical communities involved in the management of AR patients. These guidelines have been prepared in line with existing international guidelines to provide evidence-based recommendations for the diagnosis and management of AR in China.

show abstract

Section: Treatmentmentioning

confidence: 99%

Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Cheng

Chen

et al. 2018

Allergy Asthma Immunol Res

261

198

View full text Add to dashboard Cite

show abstract

“…Table 1 reports the absolute increased incidence of elevated IOP among the included studies, Table 2 reports the incidence of glaucoma, and Table 3 reports the absolute increased incidence of posterior subcapsular cataract. Overall, the patient population included patients older than 18 years of age, except for the studies conducted by Berger et al 37 and Igarashi et al 38 which included adolescents. All patients had a diagnosis of rhinitis.…”

Section: Resultsmentioning

confidence: 99%

“…There were only two studies 37,39 that assessed ocular changes with first generation INCS (beclomethasone). The majority of studies mentioned use of tonometry to assess IOPs but the exact tools were varied and included use of a noncontact tonometer, 38 tonopen, 39 Goldmann applanation tonometer. 34,40 Only one studied obtained IOP measurements at the same time of day.…”

Section: Resultsmentioning

confidence: 99%

“…31,32,35 The overall incidence of glaucoma was 0/2837, with a one-sided upper 95% confidence limit of 0.1% as calculated by Rumke’s rule. 41 Among the four studies that assessed for posterior subcapsular cataract formation, only two studies 31,40 used the Lens Opacity Classification System (LOCS III), 42 while the other two studies 37,38 used an ophthalmologist or licensed optometrist to perform a fundoscopic examination. The absolute increased incidence of patients developing a posterior subcapsular cataract while using INCS versus placebo was not significant (Table 3).…”

Section: Resultsmentioning

confidence: 99%

“…Classification System (LOCS III), 42 whereas the other two studies 37,38 used an ophthalmologist or licensed optometrist to perform a fundoscopic examination. The absolute increased incidence of patients developing a posterior subcapsular cataract while using INCS versus placebo was not significant (Table III).…”

Section: Systematic Reviewmentioning

confidence: 99%

See 2 more Smart Citations

Intranasal Corticosteroids Do Not Lead to Ocular Changes: A Systematic Review and Meta‐analysis

et al. 2018

View full text Add to dashboard Cite

Use of INCS is not associated with a significant risk of elevating IOP or developing a posterior subcapsular cataract in patients with allergic rhinitis. Presence of glaucoma, however, is the real clinical adverse event of concern. There were zero reported cases of glaucoma at 12 months. Future studies should formally evaluate for glaucoma rather than use IOP measures as a surrogate. Laryngoscope, 2018.

show abstract

Intranasal antihistamines and corticosteroids in allergic rhinitis: A systematic review and meta-analysis

Sousa-Pinto,

Vieira,

Brozek

et al. 2024

Journal of Allergy and Clinical Immunology

View full text Add to dashboard Cite

Mometasone Furoate Nasal Spray Relieves the Ocular Symptoms of Seasonal Allergic Rhinoconjunctivitis

Cited by 8 publications

References 17 publications

Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Intranasal Corticosteroids Do Not Lead to Ocular Changes: A Systematic Review and Meta‐analysis

Intranasal antihistamines and corticosteroids in allergic rhinitis: A systematic review and meta-analysis

Contact Info

Product

Resources

About