Monarticular juvenile rheumatoid arthritis

Cassidy, James T.; Brody, Gerald L.; Martel, William

doi:10.1016/s0022-3476(67)80259-2

Cited by 86 publications

(54 citation statements)

References 7 publications

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“…One out of every 5 patients with a rnonarticular onset as well as those with a disease course of oligoarthritis (pau-c i ar t ic ul ar disease) eventually developed the ocular inflammation. This level of incidence corroborates other studies: iridocyclitis occurred in l8yo of 33 monarticularonset patients observed by Bywaters and Ansell (7), in 15% of 40 monarticularonset patients by Cassidy and associates (8), and in 29y0 of 24 patients with pauciarticular disease by Schaller et al (9).…”

Section: Discussionsupporting

confidence: 91%

Chronic iridocyclitis in juvenile rheumatoid arthritis

Calabro

Parrino

Atchoo

et al. 1970

Arthritis & Rheumatism

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During a 10-year period, chronic iridocyclitis occurred in 8 of 100 patients with juvenile rheumatoid arthritis. It was an initial manifestation in 1 patient and occurred 1-8 years after onset in 7. Three patients had a recurrence. Children at greatest risk have the least arthritis. For early detection of the frequently insidious and recurrent iridocyclitis, regular slit lamp examinations are recommended to help prevent blindness due to band keratopathy and/or cataract.

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Section: Discussionsupporting

confidence: 91%

Chronic iridocyclitis in juvenile rheumatoid arthritis

Calabro

Parrino

Atchoo

et al. 1970

Arthritis & Rheumatism

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“…Other reports describe extension in 10-50% of children with oligoarthritis (JRA, JCA, or JIA) (2,5,9,10,20), but these studies included patients followed up for Ͻ5 years. Patients with disease resolution within 5 years are more likely to have been lost to longer followup, and not including this patient population may have been a bias in the present study.…”

Section: Discussionmentioning

confidence: 99%

The early pattern of joint involvement predicts disease progression in children with oligoarticular (pauciarticular) juvenile rheumatoid arthritis

Al-Matar

Petty

Tucker

et al. 2002

Arthritis & Rheumatism

117

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Objective. To evaluate features during the first 6 months of disease that may be associated with a poor outcome as measured principally by extension to a polyarticular disease course in patients with oligoarticularonset juvenile rheumatoid arthritis (oligo-JRA).Methods. This study was a retrospective review of patients who fulfilled the American College of Rheumatology criteria for oligo-JRA, were followed up for at least 5 years, and did not have juvenile psoriatic arthritis, spondylarthropathy-like disease, or rheumatoid factor positivity. Data from the first 6 months of disease were collected. Continuous variables were dichotomized and then screened by univariate analysis for association with poor outcome at the last followup visit, as measured by extension of involvement (>4 accumulated involved joints) and by "clinically meaningful" extension (>10 accumulated joints). Variables significantly associated with this latter outcome, with the addition of disease duration as a confounding independent variable, were included in a multiple logistic regression analysis. The same variables were then examined in separate multiple logistic regression models to look at other measures of outcome, including use of diseasemodifying antirheumatic drugs (DMARDs) at any time, erosive disease on radiographs, any remission of disease ever occurring, physician's global assessment of disease activity at the last visit, and disability as measured by the Childhood Health Assessment Questionnaire (C-HAQ)/HAQ. Results.Of the 205 patients (160 of whom were female) studied for a median of 10.8 years (range 5-26.6 years), 39.5% developed extension to >4 joints and 17.6% developed arthritis in >10 joints. Using the logistic regression model, symmetric disease was predictive of all measures of poor outcome: extension to >10

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“…However, this difference may be due to the fact that, in the study of those authors, only two patients were using corticosteroids. If we consider that the mineral bone density is diminished in the polyarticular type, with and without the disease activity (Cassidy & Petty, 1995), we can raise the hypothesis of Cu mobilization from bone: once in the tissue, the mineral is probably found adsorbed to the crystals (Hilário et al, 1991). This could also help to explain the increased serum copper levels in JRA, particularly in the polyarticular type.…”

Section: Serum Coppermentioning

confidence: 99%

Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

et al. 2003

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Objective: To evaluate the copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis (JRA), considering the pauci and polyarticular types, the disease activity and duration, the number of inflamed joints and the use of corticosteroids therapy. Design: Cross-sectional study with control group. Setting: Outpatients of the pediatric rheumatology public health clinic, of the Universidade Federal de São Paulo=Escola Paulista de Medicina, Brazil. Subjects: Forty-one patients with JRA were evaluated and 23 patients' brothers, as a control group. Interventions: Copper and zinc intake evaluation by Food Register method. Copper and zinc serum levels by atomic absorption spectrophotometry. Results: The disease activity did not determine difference in copper (P ¼ 0.624) and zinc (P ¼ 0.705) intake, being predominantly below the Recommended Dietary Allowances. The serum copper in relation to control was statistically greater (P ¼ 0.018), showing that the number of inflamed joints is statistically significantly related with its variation (P ¼ 0.001). The serum zinc was not different either in relation to control (P ¼ 0.940) or to the disease characteristics. Conclusions: The evaluation of copper intake seems to be of fundamental importance. It may influence the efficiency of the organic serum response. More research is needed to indicate, with security, adequate zinc intake.

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Monarticular juvenile rheumatoid arthritis

Cited by 86 publications

References 7 publications

Chronic iridocyclitis in juvenile rheumatoid arthritis

Chronic iridocyclitis in juvenile rheumatoid arthritis

The early pattern of joint involvement predicts disease progression in children with oligoarticular (pauciarticular) juvenile rheumatoid arthritis

Copper and zinc intake and serum levels in patients with juvenile rheumatoid arthritis

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