Mongoose rabies in southern Africa: a re-evaluation based on molecular epidemiology

Nel, Louis Hendrik; Sabeta, Claude; Teichman, B. von; Jaftha, Julian Bernard; Rupprecht, Charles E.; Bingham, John

doi:10.1016/j.virusres.2004.12.003

Cited by 95 publications

(99 citation statements)

References 29 publications

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“…1). Similar patterns of geographical distributions based on analysis of the G-CD and Psi-L regions were reported in southern African (28) and in Israel and Middle Eastern countries (8). Our results indicate that the Indian RV isolates studied are genetically related to one another (average nucleotide similarity, Ͼ95%).…”

Section: Analysis Of G-cd Regionsupporting

confidence: 75%

“…Nucleotide sequence analysis permits the most precise definition of virus type and helps in understanding the transmission of rabies virus from the reservoir host to other hosts, including humans and domestic animals. To date, molecular epidemiological studies of rabies viruses have been performed by sequencing different regions of RV genomes (4,5,8,13,14,15,24,26,27,28,29,30,32,33,36,42). This report describes the genetic characterization of Indian RV isolates through nucleotide sequencing of the G-CD region and of the noncoding G-L intergenic region (Psi) and the L region (Psi-L region).…”

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confidence: 99%

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Molecular Epidemiology of Rabies Virus Isolates in India

et al. 2006

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In India, rabies is enzootic and is a serious public health and economic problem. India has a large population of stray dogs which, together with a lack of effective control strategies, might have led to the persistence of rabies virus (RV) in the canine population. Our objective was to study the molecular epidemiology of RV isolates in India based on nucleotide sequence analysis of 29 RV isolates originating from different species of animals in four states. Here we have analyzed two sets of sequence data based upon a 132-nucleotide region of the cytoplasmic domain (CD) of the G gene (G-CD) and a 549-nucleotide region (Psi-L) that combines the noncoding G-L intergenic region (Psi) and a fragment of the polymerase gene (L). Phylogenetic analysis revealed that the RV isolates belong to genotype 1 and that they were related geographically but were not related according to host species. Five different genetic clusters distributed among three geographical regions were identified. Comparison of the deduced amino acid sequences of G-CD between RV isolates revealed three amino acid changes (amino acid 462G [aa462G], aa465H, and aa468K) that distinguished the Indian RVs from RV isolates in other parts of the world. Analysis of the data indicated that the dog rabies virus variants are the major circulating viruses in India that transmit the disease to other domestic animals and humans as well.

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Section: Analysis Of G-cd Regionsupporting

confidence: 75%

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confidence: 99%

Molecular Epidemiology of Rabies Virus Isolates in India

et al. 2006

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“…These organisms are presented in detail in Tables 1-7. Of the ten viruses reported for Viverridae (Table 1), three were zoonoses of considerable public health significance. These were the SARS coronavirus (SARS CoV) (Guan et al, 2003;Poon et al, 2005); HPAI H5N1 (Roberton et al, 2006;Wu et al, 2013) and a number of variants of the rabies virus (Enurah et al, 1988a;Wilde et al, 1991;Tremlett et al, 1994;Nel et al, 2005;Susetya et al, 2008;Pfukenyi et al, 2009;Matsumoto et al, 2011). Three important viruses of domestic carnivores were also reported, including canine distemper virus (CDV) (Machida et al, 1992;Hur et al, 1999;Chandra et al, 2000;L opez-Peña et al, 2001;Hirama et al, 2004;Chen et al, 2007;Takayama et al, 2009), feline parvovirus (caused by the feline panleukopenia virus, FPV) (Ikeda et al, 1999;Demeter et al, 2009) and canine parvovirus (CP) (Santos et al, 2009;Xiao-Ying et al, 2011;Duarte et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

Potential Pathogens Reported in Species of the Family Viverridae and Their Implications for Human and Animal Health

Wicker

Canfield

Higgins

2016

Zoonoses and Public Health

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Impacts• First collation of previously published organisms isolated from species of the family Viverridae provides baseline information to assist viverrid population management.• Summarizes anthropogenic factors (trade, farming, encroachment on viverrid habitat) bringing viverrids into proximity with humans.• Discusses detected organisms in terms of potential risk for public health given the described anthropogenic factors which facilitate transmission and spillover of organisms between and amongst animals and people. SummaryThe Viverridae is a family of nocturnal carnivores including civets, genets and African linsangs. While a list of known organisms isolated from a species is an essential tool for population management, this review represents the first attempt to collate published reports of organisms isolated from viverrids. A wide range of organisms, including 11 viruses, eight bacterial species, one internal arthropod species, representatives from eight genera of protozoan, 21 genera of nematode, seven genera of cestode, eight genera of trematode and six genera of external arthropod (mites, ticks and louse), have been reported in literature spanning over a century of research. Many of these are capable of infecting multiple hosts, including humans. This is of concern given the anthropogenic factors that bring humans and domestic species into close contact with viverrids, facilitating transmission and spillover of organisms between groups. These factors include trade in viverrids for human consumption, captive management in zoos, rescue centres or on commercial breeding farms, and the increasing overlap of free-ranging viverrid distribution and human settlement.

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“…Samples were selected based on previous phylogenetic studies to be representative of different phylogenetic groups within each genotype (Nel et al 2005;Sabeta et al 2007;Cohen, Sartorius, Sabeta, Zulu, Paweska, Mogoswane, Sutton, Nel, Swanepoel, Leman, Grobbelaar, Dayson & Blumberg 2007;Markotter, Kuzmin, Rupprecht & Nel 2008).…”

Section: Samplesmentioning

confidence: 99%

Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material

Markotter¹,

York²,

Sabeta³

et al. 2009

Onderstepoort J Vet Res

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<span style="font-family: arial,helvetica;">Rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously established phylogenetic groups from each genotype were included. The specificity of the rapid immunodiagnostic test compared favourably with the FAT and was found to detect all representatives of genotypes 1, 2, 3 and 4 in brain samples of either field cases or suckling mouse brain inoculates.</span>

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Mongoose rabies in southern Africa: a re-evaluation based on molecular epidemiology

Cited by 95 publications

References 29 publications

Molecular Epidemiology of Rabies Virus Isolates in India

Molecular Epidemiology of Rabies Virus Isolates in India

Potential Pathogens Reported in Species of the Family Viverridae and Their Implications for Human and Animal Health

Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material

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