Monitoring Chemical and Physical Stress Using Sea Urchin Immune Cells

Matranga, Valeria; Pinsino, Annalisa; Celi, Monica; Natoli, Anthony; Bonaventura, Rosa; Schröder, Heinz C.; Müller, Wernér E.G.

doi:10.1007/3-540-27683-1_5

Cited by 97 publications

(97 citation statements)

References 64 publications

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“…In fact, they are involved in: clot formation, phagocytosis, encapsulation and clearance of pathogens, as well as oxygen transport. The coelomic fluid in which the immunocytes or coelomocytes reside and move is a key factor governing the immunological capabilities of echinoderms, as it contains essential trophic and activating factors (for a review see Matranga et al, 2005;Smith et al, 2010). Four different morphotypes have been described in the asteroid Asterias rubens, with the phagocytes as the most abundant type, accounting for approximately 95% of the total population (Pinsino et al, 2007).…”

Section: How Does Manganese Affect Echinoderm Immune Cells?mentioning

confidence: 99%

Manganese: A New Emerging Contaminant in the Environment

Pinsino¹,

Matranga²,

Roccheri³

2012

Environmental Contamination

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Section: How Does Manganese Affect Echinoderm Immune Cells?mentioning

confidence: 99%

Manganese: A New Emerging Contaminant in the Environment

Pinsino¹,

Matranga²,

Roccheri³

2012

Environmental Contamination

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“…In the sea urchin, both coelomic fluid and coelomocytes have been shown to contain the precursor of toposome (Cervello and Matranga 1989;Cervello et al 1994), an adhesive molecule previously identified in embryos, whose biological role in mediating cellular adhesion has been fully documented (Matranga et al 1986;Scaturro et al 1998). Sea urchin coelomocytes also have been shown to have increased Hsp70 levels in response to temperature stress, acidic pH, heavy metals, and other pollutants (Matranga et al 2000(Matranga et al , 2005(Matranga et al , 2006. The function of Hsp proteins in a number of intracellular processes, such as chaperone guidance (Becker and Craig 1994), protein folding (Buchner 1996), and protection against apoptosis (Parcellier et al 2003), explains their high evolutionary conservation.…”

Section: Introductionmentioning

confidence: 99%

“…The origins, cell lineage regulation, and fate of freely circulating coelomocytes (the immune cells of echinoderms), is receiving increased attention for several important reasons: (1) their relationship to vertebrate homologues (Smith and Davidson 1994;Hibino et al 2006), (2) Thorndyke et al 2001), and (4) the availability of genomic tools to analyze regulative functions (Matranga et al 2005;Hibino et al 2006;Sea Urchin Genome Sequencing Consortium 2006). Coelomocytes are found in the coelomic spaces of all echi-noderms, including the perivisceral coelomic cavities, the water-vascular system, and the hemal system, as well as in the connective tissue and amongst tissues of various organs (Glinski and Jarosz 2000; see Muñ oz-Chápuli et al 2005 for a review).…”

Section: Introductionmentioning

confidence: 99%

“…Coelomocytes are found in the coelomic spaces of all echi-noderms, including the perivisceral coelomic cavities, the water-vascular system, and the hemal system, as well as in the connective tissue and amongst tissues of various organs (Glinski and Jarosz 2000; see Muñ oz-Chápuli et al 2005 for a review). They participate in functions similar to their immune system homologues in vertebrates, such as formation of cellular clots, phagocytosis, encapsulation and clearance of bacteria and other foreign materials, as well as oxygen transport (for a review see Matranga et al 2005). So far there is no common opinion about the origin of circulating coelomocytes.…”

Section: Introductionmentioning

confidence: 99%

“…Unfortunately, these ideas have received little recent attention. Some more recent studies have shown a rapid increase in the numbers of red amoebocytes, a minor group of sea urchin coelomocytes, accounting for 5% of the total population, in response to pollution or experimentally induced stress (Matranga et al 2000(Matranga et al , 2005. This evidence can be explained by either the rapid division of circulating stem cells or by their recruitment from the coelothelium, axial organ, or other niches.…”

Section: Introductionmentioning

confidence: 99%

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Coelomocytes and post-traumatic response in the common sea star Asterias rubens

Pinsino¹,

Thorndyke²,

Matranga³

2007

Cell Stress Chaper

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Coelomocytes are recognized as the main cellular component of the echinoderm immune system. They are the first line of defense and their number and type can vary dramatically during infections or following injury. Sea stars have been used as a model system to study the regeneration process after autotomy or predation. In the present study we examined the cellular and biochemical responses of coelomocytes from the European sea star Asterias rubens to traumatic stress using immunochemical and biochemical approaches. In terms of trauma and post-traumatic stress period, here we consider the experimental arm amputation and the repair phase involved in the first 24 hours postamputation, which mimicked a natural predation event. Four cell morphotypes were distinguishable in the coelomic fluid of both control and post-traumatic-stressed animals (phagocytes, amoebocytes, vibratile cells, hemocytes), but phagocytes were the major components, accounting for about 95% of the total population. Thus, the effects measured relate to the overall population of coelomocytes. A modest increase in the total number of freely circulating coelomocytes was observed 6 hours post-amputation. Interestingly, a monoclonal antibody (McAb) to a sea urchin embryo adhesion protein (toposome) cross-reacted with isolated sea star coelomocytes and stained the coelomic epithelium of control animals with an increase in trauma-stressed arms. In addition, coelomocytes from trauma-stressed animals showed a time-dependent increase in Hsp70 levels, as detected by both immunocytochemistry and immunoblotting within 24 hours after arm tip amputation, with a peak at 6 hours after amputation. Our findings indicate a clear role for coelomocytes and classic stress molecules in the post-traumatic stress associated with the early repair phase of regeneration.

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How ocean warming and acidification affect the life cycle of six worldwide commercialised sea urchin species: A review

Olivier

Chauvaud

Tremblay

2023

Aquaculture Fish & Fisheries

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Ongoing global changes are expected to affect the worldwide production of many fisheries and aquaculture systems. Because invertebrates represent a relevant industry, it is crucial to anticipate challenges that are resulting from the current environmental alterations. In this review, we rely on the estimated physiological limits of six commercialised species of sea urchins (Loxechinus albus, Mesocentrotus franciscanus, Paracentrotus lividus, Strongylocentrotus droebachiensis, Strongylocentrotus intermedius and Strongylocentrotus purpuratus) to define the vulnerability (or resilience) of their populations facing ocean warming and acidification (OW&A). Considering that coastal systems do not change uniformly and that the populations’ response to stressors varies depending on their origin, we investigate the effects of OW&A by including studies that estimate future environmental mutations within their distribution areas. Cross‐referencing 79 studies, we find that several sea urchin populations are potentially vulnerable to the predicted OW&A as environmental conditions in certain regions are expected to shift beyond their estimated physiological limit of tolerance. Specifically, while upper thermal thresholds seem to be respected for L. albus along the SW American coast, M. franciscanus and S. purpuratus southern populations appear to be vulnerable in NW America. Moreover, as a result of the strong warming expected in the Arctic and sub‐Arctic regions, the local productivity of S. droebachiensis is also potentially largely affected. Finally, populations of S. intermedius and P. lividus found in northern Japan and eastern Mediterranean respectively, are supposed to decline due to large environmental changes brought about by OW&A. This review highlights the status and the potential of local adaptation of a number of sea urchin populations in response to changing environmental conditions, revealing possible future challenges for various local fishing industries.

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Monitoring Chemical and Physical Stress Using Sea Urchin Immune Cells

Cited by 97 publications

References 64 publications

Manganese: A New Emerging Contaminant in the Environment

Manganese: A New Emerging Contaminant in the Environment

Coelomocytes and post-traumatic response in the common sea star Asterias rubens

How ocean warming and acidification affect the life cycle of six worldwide commercialised sea urchin species: A review

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