Abstract. In recent years, with the development of fisheries, the aquaculture industry has developed rapidly and has become an important part of our country economy. At the same time more and more aquatic products is being used by people while the abuse of antibiotics is growing uncontrolled. This paper summarizes the detection methods of various kinds of antibiotics in aquatic products, as well as the method of spiked recovery, detection limit, quantitative limit, and puts forward the corresponding countermeasures proposal of controlling the abuse of antibiotics.