Monitoring of apixaban in a super-obese patient: impact of renal failure and topical application of econazole

Abstract

Direct oral anticoagulants (DOACs) are considered advantageous compared with vitamin K antagonists in eligible atrial fibrillation patients [1]. The efficacy and the safety of DOACs are not well defined in the morbidly obese population. A recent meta-analysis showed that, compared with warfarin therapy, the use of DOACs was not associated with a higher event rate of stroke or systemic embolism in morbidly obese patients with atrial fibrillation, but with a significantly