Monitoring of arsenic exposure with speciated urinary inorganic arsenic metabolites for ion implanter maintenance engineers

Hwang, Yaw-Huei; Lee, Zhih-Young; Wang, Jung‐Der; Hsueh, Yu Mei; Lu, I-Chun; Yao, Wan-Lin

doi:10.1016/s0013-9351(02)00005-1

Cited by 19 publications

(17 citation statements)

References 23 publications

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“…Although most of these applications have been discontinued, residues from such activities, together with the ongoing generation from the smelting of various ores, have left a large quantity of heavy-metal wastes [14,15]. Occupational exposure to inorganic As, arsenites (As 3 ) and arsenates (As 5 ) occurs in the manufacture and/or processing of many products, for example in non-ferrous metal foundries, the production of artistic glass, coalfired power plants, the manufacture of semiconductors, the production and use of pesticides and wood preservatives [6,16]. In all these cases, As is absorbed essentially by inhalation, although the extent of this process depends on the size of particulate matter where As is adsorbed and on the solubility of the chemical form of inorganic As [6,17].…”

Section: Introductionmentioning

confidence: 99%

Levels of Arsenic, Cadmium, Lead, Manganese and Zinc in Biological Samples of Paralysed Steel Mill Workers with Related to Controls

Afridi

Kazi

et al. 2011

Biol Trace Elem Res

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The determination of essential trace and toxic elements in the biological samples of human beings is an important clinical screening procedure. This study aimed to assess the possible effects of environmental exposure on paralysed male workers (n = 75) belonging to the production and quality control departments of a steel mill. In this investigation, the concentrations of arsenic, cadmium, lead, manganese and zinc were determined in biological samples (blood, urine and scalp hair samples) of exposed paralysis and non-paralysed steel mill workers. For comparative purposes, unexposed healthy subjects of same age group were selected as referents. The elements in the biological samples were measured by atomic absorption spectrophotometry prior to microwave-assisted acid digestion. The validity of the methodology was checked by the biological certified reference materials. The results indicate that the level understudy elements in all three biological samples were significantly higher in paralysed workers of both groups (quality control and production) as compared to referents (p < 0.01). The possible connection of these elements with the aetiology of disease is discussed. The results also show the need for immediate improvements of workplace ventilation and industrial hygiene practices.

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Section: Introductionmentioning

confidence: 99%

Levels of Arsenic, Cadmium, Lead, Manganese and Zinc in Biological Samples of Paralysed Steel Mill Workers with Related to Controls

Afridi

Kazi

et al. 2011

Biol Trace Elem Res

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“…During processing, arsenic-containing byproducts, such as arsenic trioxide, could possibly deposited on the inside reaction chamber surfaces. These by-products can generate the particulate matter-bound arsenic (PMAs), which may therefore pose a potential arsenic exposure risk to workers through the inhalation or dermal contact while performing their tasks [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

“…In Taiwan, operators at a semiconductor manufacturing facility were exposed to higher levels of PMAs ranging from 5.26 to 106.12 g m −3 [5]. Hwang et al [4] also pointed out that the concentration of total urinary arsenic metabolites showed significant increasing trend for ion implanter maintenance engineers. Despite much evidence indicated that higher levels of occupation arsenic exposure for semiconductor workers, little is known about PMAs in semiconductor manufacturing facility by which a potential health risk to workers working in the facility may pose.…”

Section: Introductionmentioning

confidence: 99%

Assessing airborne PM-bound arsenic exposure risk in semiconductor manufacturing facilities

Chou

Chio

Liao

2009

Journal of Hazardous Materials

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“…Previous biological monitoring studies have shown that As 3+ , As 5+ , the sum of inorganic arsenic (As 3+ + As 5+ ), and the sum of inorganic arsenic and monomethylarsonic acid (MMA) were higher in ion implanter PM engineers than in a non-exposed group after adjusting for smoking and seafood intake (Byun et al, 2013). Monitoring urinary arsenic by using the percentage change of MMA in total urinary inorganic arsenic metabolites as an indicator for the verification of arsenic exposure is helpful and appropriate for ion implanter PM workers (Hwang et al, 2002). A case control study showed that the mean urinary concentration of total arsenic was significantly higher in arsenic-exposed workers than in non-exposed workers (Hu et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

Arsenic Exposure during Preventive Maintenance of an Ion Implanter in a Semiconductor Manufacturing Factory

Ham

Yoon

Kim

et al. 2017

Aerosol Air Qual. Res.

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Workers in the semiconductor fabrication process may be exposed to higher levels of hazardous materials, such as arsenic, during preventive maintenance (PM) tasks than during the regular operation of the fabrication process. This study investigates the exposure to arsenic and other metals during PM tasks in the ion implantation process. Airborne arsenic samples and bulk samples were obtained during various ion implanter PM tasks in a semiconductor fabrication factory. The arithmetic mean (AM) and standard deviation (SD) of airborne arsenic in personal samples were 0.64 µg m -3 ± 0.92 µg m -3 (n = 9), and the highest level was 2.39 µg m -3 during medium-current ion implanter PM tasks. For area samples, the AM and SD were 0.42 µg m -3 ± 0.69 µg m -3 (n = 5) and the highest level was 1.79 µg m -3 during medium-current ion implanter PM tasks. Arsenic was also found in the bulk samples of debris produced during PM tasks. Other metals (Ag, Al, Cu, Pb, Cr, Sn, Mn, Ti, Fe, and W) were found, but at low levels, prompting few health concerns compared with those of arsenic. This study found that PM workers were exposed to airborne arsenic levels that differed significantly according to the type of ion implanter used.

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Monitoring of arsenic exposure with speciated urinary inorganic arsenic metabolites for ion implanter maintenance engineers

Cited by 19 publications

References 23 publications

Levels of Arsenic, Cadmium, Lead, Manganese and Zinc in Biological Samples of Paralysed Steel Mill Workers with Related to Controls

Levels of Arsenic, Cadmium, Lead, Manganese and Zinc in Biological Samples of Paralysed Steel Mill Workers with Related to Controls

Assessing airborne PM-bound arsenic exposure risk in semiconductor manufacturing facilities

Arsenic Exposure during Preventive Maintenance of an Ion Implanter in a Semiconductor Manufacturing Factory

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