Monitoring of selected estrogenic compounds and estrogenic activity in surface water and sediment of the Yellow River in China using combined chemical and biological tools

Wang, Li; Ying, Guang‐Guo; Chen, Feng; Zhang, Lijuan; Zhao, Jian‐Liang; Lai, Hua‐Jie; Chen, Zhifeng; Tao, Ran

doi:10.1016/j.envpol.2011.10.005

Cited by 132 publications

(41 citation statements)

References 71 publications

(104 reference statements)

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“…The concentrations of BPA in ZR, DR, and XR, and in the adjacent rivers of Jiaozhou Bay were at similar levels (Li et al, 2006;Fu et al, 2007), but much higher than those in other domestic rivers. In addition, both the E1 and E2 concentrations in the four rivers from the PRD were low, and similar to those in the Lanzhou reach of the Yellow River (Wang et al, 2012).…”

Section: Level Of Contamination By Phenolic Xenoestrogens Along Side mentioning

confidence: 89%

Seasonal variation and partitioning of endocrine disrupting chemicals in waters and sediments of the Pearl River system, South China

Gong

Duan

Yang

et al. 2016

Environmental Pollution

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Section: Level Of Contamination By Phenolic Xenoestrogens Along Side mentioning

confidence: 89%

Seasonal variation and partitioning of endocrine disrupting chemicals in waters and sediments of the Pearl River system, South China

Gong

Duan

Yang

et al. 2016

Environmental Pollution

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“…However, if a variety of ligands exist simultaneously, the behavior between them and ERs may change due to their different concentrations and receptor binding abilities, both of which are critical influences on the final effects. The nine selected substances have frequently been found, by chemical analysis, at relatively high concentrations in the aquatic system of China, and all of them have been associated with endocrine disrupting effects (Gong et al, 2012;Lei et al, 2009;Liu et al, 2012;Lu et al, 2010;Sun et al, 2008;Wang et al, 2012;Yan et al, 2012;Ye et al, 2012). Thus, we chose them as representative estrogen-like chemicals that are present in the water environment.…”

Section: Discussionmentioning

confidence: 99%

Combined effects of estrogenic chemicals with the same mode of action using an estrogen receptor binding bioassay

Yang

et al. 2014

Environmental Toxicology and Pharmacology

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“…In comparison to the Liao and the Pearl River systems, the Yellow River poses a lower risk from the presence of the EDCs. Of 15 sites sampled in the Yellow River, only one site had an EEQ higher than 0.73 ng/L (Wang et al 2012). Estrogenic effects of surface water and sediments from the Liao, Yellow, and Pearl Rivers were also assessed by using an in vitro bioassay (YES: yeast estrogen screen).…”

Section: Risk Assessment Of Ambient Concentrations In Chinamentioning

confidence: 99%

Predicted No-Effect Concentration and Risk Assessment for 17-[Beta]-Estradiol in Waters of China

Fang

et al. 2013

Reviews of Environmental Contamination and Toxicology

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Contamination of the aquatic environment by EDCs has received considerable attention from scientists, government officials, and the public. E2, one of the EDCs with high estrogenic effect, has the potential to cause multiple endocrine-disrupting effects, even at small concentrations. In the present review, the toxicity of E2 to aquatic organisms was reviewed. Results of published studies show that, for aquatic species, reproductive effects were the most sensitive endpoint for E2 exposure.Although the risks posed by EDCs have caused much attention, the research on the WQC 'for EDCs is still at the initial stage. It has been suggested in several reports that the PNEC can be regarded as the most appropriate reference value for developing WQC for the EDCs. The SSD method was applied to derive PNECs that were based on reproductive effects endpoints. In the present review, 31 NOECs, based on reproductive effect endpoints for different species, were selected to construct the curve. ThePNEC value was determined to be 0.73 ng E2/L, which could protect the biodiversity of aquatic ecosystems. Moreover, 6 NOECs for multigeneration species were also analyzed in anticipation of sensitivity comparison between the Fa and the F1 generations.When multiple generations of aquatic species were exposed to concentrations no greater than 100 ng E2/L, nearly 71.4% of the F 1 generation individuals were more sensitive to the effects of E2 than those of the Fa generation. This result indicated that different generations of the same species may respond differently to EDCs exposure.Individuals of the F 1 generation were slightly more sensitive than those of the Fa generation,in general. Therefore, protecting the F1 generation of aquatic organisms is particularly important when WQC values for the EDCs are established.Considering the toxic effects of EDCs on reproduction, long-term toxic effects(viz., full-life cycle study and the most sensitive life stage) should be used in settingWQC. Unfortunately, the NOECs of E2 for multigeneration species did not meet the requirement of PNEC derivation for protecting the Fl generation. Therefore, further research results are needed on the Fl generation of aquatic species to provide more insight into what constitutes adequate protection for aquatics lives. In the present review, the PNEC values derived in the study were compared to thePNEC values developed by others, and the results showed that they were highly consistent. In addition, we also compared the PNEC value for E2 to the PNEC value for EE2, a similar estrogen, and the result was also highly consistent when their EEFs were considered. These comparisons affirmed that the method we used for deriving the PNEC value of E2 was reasonable and the PNEC values we derived were acceptable for protecting aquatic organisms. By comparing the PNEC values we calculated to actual E2 concentrations in the natural water environment, we found that E2 in surface waters may pose high risks in many countries, especially China, Japan, the USA, Great Britain, and Italy.

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Monitoring of selected estrogenic compounds and estrogenic activity in surface water and sediment of the Yellow River in China using combined chemical and biological tools

Cited by 132 publications

References 71 publications

Seasonal variation and partitioning of endocrine disrupting chemicals in waters and sediments of the Pearl River system, South China

Seasonal variation and partitioning of endocrine disrupting chemicals in waters and sediments of the Pearl River system, South China

Combined effects of estrogenic chemicals with the same mode of action using an estrogen receptor binding bioassay

Predicted No-Effect Concentration and Risk Assessment for 17-[Beta]-Estradiol in Waters of China

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