Monitoring the Practice of Vascular Surgery: Findings from a National Registry (1996–2011)

Lozano, Francisco; Marinello, J; Moreno, Rosa Martínez; Aguilar, María del Mar Escalante; López-Quintana, A.; González‐Porras, José Ramón; Alvarez, Javier García; Giménez-Gaibar, Antonio; Alguacil, Rafael; Cairols, M; Marco-Luque, Miguel A.; Vaquero, F; Callejas, J.M.

doi:10.1007/s00268-013-2272-6

Cited by 8 publications

(3 citation statements)

References 35 publications

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“…Sin embargo, en la práctica clínica habitual, las continuas mejoras de las técnicas endovasculares, están propiciando año tras año (fundamentalmente debidas a su menor agresividad y menor morbi-mortalidad a corto plazo) un desplazamiento de la cirugía abierta, máxime en octogenarios donde muchos de estos pacientes (más por comorbilidad que por edad) quedaban excluidos para cirugía abierta (10).…”

Section: Tratamiento Actual De Los Aaaunclassified

Treatment of aneurysms of the abdominal aorta. Improvements and evidences

Sánchez

2022

an. ranm

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A review of the literature on aortic aneurysms is carried out, focusing on abdominal aortic aneurysms as the most frequent location. After introducing the topic (concept, frequency, natural history of the disease, consequences -mortality-, etc.), the review focuses on the individualized treatment of this entity and the improvements obtained during the last decade, both in elective and non-elective situations, which have led to a reduction in mortality. These improvements are due to several components such as: a) early diagnosis (screening effect) and correct follow-up of aneurysms (using echo-Doppler) that have made it possible to increase more elective surgeries and reduce urgent surgeries; b) control of cardiovascular risk factors, mainly tobacco and the use of statins in this type of patient; c) the role of endovascular surgery, which has made it possible to expand surgical indications to patients previously not eligible for open surgery, including nonagenarians and some centenarians; and d) to the effect of centralizing the most complex cases (the higher the volume, the better the results).

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Section: Tratamiento Actual De Los Aaaunclassified

Treatment of aneurysms of the abdominal aorta. Improvements and evidences

Sánchez

2022

an. ranm

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“…Varicose veins (VV) record a high prevalence in western societies [1], featuring among the Top-10 most common surgical procedures and involving the longest waiting lists for operations in public health systems [2][3]. All-in-all, VV constitute the perfect storm of clinical, social and economic problems; some examples are their associated complications (e.g., ulcers), a decrease in wellbeing, and the medical-legal issues they entail [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Endoglin and Other Angiogenesis Markers on Recurrent Varicose Veins

Sánchez¹,

Martínez²,

García³

et al. 2022

Preprint

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Background: Surgery on varicose veins (crossectomy and stripping) leads to recurrence and has clinical and socio-economic repercussions. Their etiopathogenesis has yet to fully under-stood. Objective: Study the expression of endoglin and other molecules involved in the neovascu-larisation process in patients suffering from this disease. Methods: 43 patients that have undergone surgery for varicose veins (24 primary and 19 recurrent). They were identified on the venous wall (proximal -saphenofemoral junction- and distal), via real-time RT-PCR, and in serum, via ELISA: Endoglin (Eng), Vascular Endothelial Growth Factor (VEGF-A), its receptors 1 and 2 (VEGFR1 or FLT1), (VEGFR2 or FLK), and the Hypoxia-Inducible Factor (HIF-1A). All the patients signed a con-sent form. Results: The recurrent group recorded a higher expression of Eng, VEGF-A, VEGFR1 and VEGFR2 at the level of proximal venous wall compared to the primary group. HIF-1A did not record any differences. As regards the determination of the distal venous wall, no markers recorded differ-ences between the groups. Among the serum determinations, only sFLT1 recorded a significant drop among the patients with recurrent varicose veins. Conclusions: Patients with recurrent vari-cose veins record a higher expression of endoglin and other markers of angiogenesis in proximal veins. Endoglin in the blood (sEng) has not proven to be of any use in recurrent varicose veins.

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“…Varicose veins (VV) are highly prevalent in western societies [1], featuring among the top ten most common surgical procedures and involving the longest waiting lists for operations in public health systems [2,3]. All-in-all, VV constitute the perfect storm of clinical, social and economic problems; some examples are their associated complications (e.g., ulcers), a decrease in wellbeing, and the medical-legal issues they entail [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Endoglin and Other Angiogenesis Markers in Recurrent Varicose Veins

Sánchez

Martínez

Méndez-García

et al. 2022

JPM

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Background: Surgery on varicose veins (crossectomy and stripping) may lead to recurrence, with clinical and socioeconomic repercussions. The etiopathogenesis of varicose veins has yet to be fully understood. Objective: Study the expression of endoglin and other molecules involved in the neovascularisation process in patients suffering from this disease. Methods: Total of 43 patients that have undergone surgery for varicose veins (24 primary and 19 recurrent). Endoglin and other molecules were identified on the venous wall (proximal -saphenofemoral junction- and distal), via real-time RT-PCR, and in serum, via ELISA: endoglin (Eng), vascular endothelial growth factor (VEGF-A), its receptors 1 and 2 (VEGFR1 or FLT1), (VEGFR2 or FLK), and the hypoxia-inducible factor (HIF-1A). All the patients signed a consent form. Results: The recurrent group recorded a higher expression of Eng, VEGF-A, VEGFR1, and VEGFR2 at the level of proximal venous wall compared to the primary group. HIF-1A did not record any differences. As regards the determination of the distal venous wall, no markers recorded differences between the groups. Among the serum determinations, only sFLT1 recorded a significant drop among the patients with recurrent varicose veins. Conclusions: Patients with recurrent varicose veins record a higher expression of endoglin and other markers of angiogenesis in proximal veins. Endoglin in the blood (sEng) serves no apparent purpose in recurrent varicose veins.

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Monitoring the Practice of Vascular Surgery: Findings from a National Registry (1996–2011)

Abstract: The SVR has enabled us to understand the development and implementation of vascular surgery throughout Spain and to note the increased healthcare activity and the better overall results obtained as a consequence.

Cited by 8 publications

References 35 publications

Treatment of aneurysms of the abdominal aorta. Improvements and evidences

Treatment of aneurysms of the abdominal aorta. Improvements and evidences

Endoglin and Other Angiogenesis Markers on Recurrent Varicose Veins

Endoglin and Other Angiogenesis Markers in Recurrent Varicose Veins

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