Monitoring the quality of life in patients with coronary artery disease

Spertus, John A.; Winder, Jennifer A.; Dewhurst, Timothy A.; Deyo, Richard A.; Fihn, Stephan D.

doi:10.1016/0002-9149(94)90555-x

Cited by 372 publications

(240 citation statements)

References 15 publications

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“…Validated standardized instruments were used to assess psychosocial and health status. These included (1) depression using the 9‐item Patient Health Questionnaire (PHQ‐9), with higher scores indicating increasing severity (range 0–27)19, 20, 21, 22; (2) perceived stress using the 14‐item Perceived Stress Scale (PSS), with higher scores indicating higher stress levels (range 0–40)23, 24; and (3) health status outcomes (patients’ physical limitations, angina frequency, and quality of life related to angina) using the Seattle Angina Questionnaire (SAQ; scores ranging from 0 to 100), with higher scores indicating better health status 25, 26, 27, 28, 29. In addition, detailed review of medical charts was conducted to better characterize the AMI phenotypes.…”

Section: Methodsmentioning

confidence: 99%

Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study

Safdar

Spatz

Dreyer

et al. 2018

JAHA

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344

233

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BackgroundWe compared the clinical characteristics and outcomes of young patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) versus obstructive disease (myocardial infarction due to coronary artery disease [MI‐CAD]) and among patients with MINOCA by sex and subtype.Methods and ResultsBetween 2008 and 2012, VIRGO (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients) prospectively enrolled acute myocardial infarction patients aged 18 to 55 years in 103 hospitals at a 2:1 ratio of women to men. Using an angiographically driven taxonomy, we defined patients as having MI‐CAD if there was revascularization or plaque ≥50% and as having MINOCA if there was <50% obstruction or a nonplaque mechanism. Patients who did not have an angiogram or who received thrombolytics before an angiogram were excluded. Outcomes included 1‐ and 12‐month mortality and functional (Seattle Angina Questionnaire [SAQ]) and psychosocial status. Of 2690 patients undergoing angiography, 2374 (88.4%) had MI‐CAD, 299 (11.1%) had MINOCA, and 17 (0.6%) remained unclassified. Women had 5 times higher odds of having MINOCA than men (14.9% versus 3.5%; odds ratio: 4.84; 95% confidence interval, 3.29–7.13). MINOCA patients were more likely to be without traditional cardiac risk factors (8.7% versus 1.3%; P<0.001) but more predisposed to hypercoaguable states than MI‐CAD patients (3.0% versus 1.3%; P=0.036). Women with MI‐CAD were more likely than those with MINOCA to be menopausal (55.2% versus 41.2%; P<0.001) or to have a history of gestational diabetes mellitus (16.8% versus 11.0%; P=0.028). The MINOCA mechanisms varied: a nonplaque mechanism was identified for 75 patients (25.1%), and their clinical profiles and management also varied. One‐ and 12‐month mortality with MINOCA and MI‐CAD was similar (1‐month: 1.1% and 1.7% [P=0.43]; 12‐month: 0.6% and 2.3% [P=0.68], respectively), as was adjusted 12‐month SAQ quality of life (76.5 versus 73.5, respectively; P=0.06).ConclusionsYoung patients with MINOCA were more likely women, had a heterogeneous mechanistic profile, and had clinical outcomes that were comparable to those of MI‐CAD patients.Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT00597922.

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Section: Methodsmentioning

confidence: 99%

Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study

Safdar

Spatz

Dreyer

et al. 2018

JAHA

Self Cite

344

233

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“…Seattle angina questionnaire (SAQ) was used to measure perceived limitation in performing physical activities (Spertus et al, 1994). The SAQ is a reliable and valid self-report instrument with 19 items that yields five subscale scores including the physical limitation subscale which measures how common daily activities are limited by angina.…”

Section: The Seattle Angina Questionnaire -Physical Limitation Subscamentioning

confidence: 99%

Gender differences in pain characteristics of chronic stable angina and perceived physical limitation in patients with coronary artery disease

Kimble

McGuire

Dunbar

et al. 2003

Pain

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Chronic stable angina pectoris, the chest pain associated with reversible myocardial ischemia has detrimental effects on health-related quality of life, particularly in women. The limited research on gender differences in chronic stable angina suggests that angina may be experienced differently in women and that women report greater functional disability related to angina symptoms. No studies have examined gender differences in chronic stable angina from a multidimensional pain perspective or have included reliable and valid measures of pain that would facilitate comparing chronic angina patients with other chronic pain populations. The purpose of this descriptive study was to examine gender differences in characteristics of chronic stable angina using the short-form McGill pain questionnaire (SF-MPQ) and to explore relationships among these pain characteristics and perceived limitation in performing physical activities in patients with coronary artery disease (CAD) (physical limitation subscale of the Seattle angina questionnaire). One hundred and twentyeight subjects (30.5% women) with stable CAD and angina pectoris documented by a cardiologist completed study questionnaires in an outpatient cardiology clinic. Results of the study suggest that men and women with chronic stable angina had more similarities than differences in chest pain characteristics. No significant gender differences were demonstrated in total sensory or affective intensity scores, the present pain intensity index, or the number of pain words chosen. However, women did report significantly greater pain intensity on the SF-MPQ visual analogue scale. Women were also significantly more likely to describe their chronic angina as 'hot-burning' and 'tender' and to have greater intensity of pain for these two descriptors. Despite the similarities in pain characteristics, women reported greater physical limitation related to anginal pain. The variables of social status and years diagnosed with CAD significantly interacted with gender in predicting physical limitation suggesting that gender-specific models of physical limitation in angina patients need to be explored. To our knowledge, this is one of the first studies that has assessed chronic anginal pain using a reliable and valid generic pain instrument. More research is needed to better understand the nature of gender differences in functional limitation secondary to anginal pain and the physiologic, cognitive-perceptual and psychosocial mechanisms that lead to angina-related functional disability.

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“…Different researchers have looked at quality of life related to coronary artery disease and the impact of its treatment on the individual's life today (2)(3)(4)(5)(6) . These studies are considered important, because, besides evaluating the therapeutic results, they generate new hypotheses and reflections that permit a broader focus in studies on quality of life, seeking methodological options in terms of the discussion of theoretical and conceptual aspects involved in the evaluation of this phenomenon.…”

Section: Introductionmentioning

confidence: 99%

Quality of life from the perspective of revascularized patients during rehabilitation: an ethnographic study

Vila

Rossi

2008

Rev. Latino-Am. Enfermagem

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Monitoring the quality of life in patients with coronary artery disease

Cited by 372 publications

References 15 publications

Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study

Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study

Gender differences in pain characteristics of chronic stable angina and perceived physical limitation in patients with coronary artery disease

Quality of life from the perspective of revascularized patients during rehabilitation: an ethnographic study

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