Preoperative autologous blood donation (PABD) can be an adequate
solution to a patient’s problem before nonurgent surgery if a
high (>10%) probability of perioperative blood transfusion exists in
this individual case and, at the same time, pre-existing alloimmunization
or a different ethnic background make it difficult to supply
this patient with compatible red blood cell concentrates. In times of
acute shortness of blood, when nonurgent surgery might be
rescheduled and delayed, and in cases of extreme angst-ridden patients
fearing homologous blood transfusion, PABD can be considered
in rare individual cases as well. Nonetheless, in all these cases,
the patient must be eligible for PABD, and the indication as well as
potential contraindications have to weighted against each other in a
thorough individual risk-benefit analysis. However, these are relatively
rare cases. Apart from these and few other situations, PABD
in our opinion should not be used because of high costs and logistic
efforts, high wastage, considerable risks for the donor/patient on
the one hand and miniscule benefits on the other hand. PABD cannot
significantly contribute to the blood supply. PABD in error-free
use, which is unrealistic, reduces the risk of transmission of known
and unknown viral pathogens, but possibly not of bacteria. In real
life situations, the residual risk for transmission of transfusion-relevant
viruses such as HIV, HVC or HBV is not diminished by PABD.
The same is true for clerical errors and ABO incompatibility or acute
hemolytic transfusion reactions due to a mix-up of products. PABD
reduces the risk of (allo)immunization and therefore has its indication
in special clinical situations. PABD on the other hand increases
the risks for the donor at the time of donation and afterwards. Autologous
blood products seem to have higher rates of bacterial contamination.
The risk for the patient to receive any transfusion perioperatively
is increased due to the lower hemoglobin levels at
admission (iatrogenic anemia) as well as due to a wrongly more
liberal transfusion strategy in autologous hemotherapy compared
to transfusion of homologous blood. A significant number of patients,
who would never receive any transfusion perioperatively at
all, enter the transfusion chain due to PABD procedures, facing the
risks of a blood donor as well as the risks of a transfusion recipient.