Mönkeberg's sclerosis: role of calcification in arterial lesions in patients with diabetes mellitus

Kulikova, A N; Толстокоров, А С; Larin, I V

doi:10.33529/angi02020406

Cited by 1 publication

(3 citation statements)

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“…Mönckeberg's medial layer calcification, though rare, should be considered in patients with peripheral obstructive arterial disease of unknown etiology and no conventional risk factors [ 7 ]. Research is needed to improve the diagnosis and treatment of this disease [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…The fluid collection and arterial calcification improved on his follow-up imaging. Due to macroangiopathies, diabetes mellitus is strongly linked to Mönckeberg's sclerosis according to Kulikova et al [ 7 ]. Our patient was medically healthy, unlike the previous study.…”

Section: Discussionmentioning

confidence: 99%

“…In patients with peripheral obstructive arterial disease of undefined etiology lacking traditional risk factors, Mönckeberg's medial layer calcification, though rare, should be considered a potential cause of peripheral vasculopathy. Further studies are needed to better understand this disease and improve diagnosis and treatment [ 7 ].…”

Section: Case Presentationmentioning

confidence: 99%

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Mönckeberg's Disease With Calcified Lower Limb Ischemia in Saudi Arabia: A Rare Case Report and Literature Review

Odah¹,

Khalid²,

Alsaati³

et al. 2023

Cureus

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Mönckeberg's disease, a rare medial calcific arteriosclerosis, predominantly affects lower extremity arteries with an unclear etiology. If untreated, severe complications like ischemic necrosis and gangrene may arise. We present a case of a 28-year-old male with spontaneous lower limb swelling, abscess, and itching. Despite a history of deep vein thrombosis and warfarin therapy, Mönckeberg's disease was suspected. Imaging revealed diffuse vascular calcification of the media of the arterial wall bilaterally in the right and left femoral vessels with heterogenous irregular soft tissue collection in the right with suspected infection. Following treatment, the patient's symptoms improved, and follow-up imaging showed resolution of fluid collections and improved calcification appearance. This report highlights the importance of considering Mönckeberg's disease in the differential diagnosis of lower extremity swelling and the need for timely management to prevent serious complications.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Case Presentationmentioning

confidence: 99%

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