Monkeypox-Associated Acute Kidney Injury and Foreseeable Impacts on Nephrology and Kidney Transplantation Services

Reis, Thiago; Neves, Francisco de Assis Rocha; Fagundes, Antônio; See, Emily J; Passos, RH; Zawadzki, Bruno; Bellomo, Rinaldo; Ronco, Claudio

doi:10.1159/000528041

Cited by 2 publications

(6 citation statements)

References 9 publications

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“…Another potential etiology that should be considered is the administration of tenofovir disoproxil fumarate (an antiretroviral medication). The medication is usually administered by HIV patients and can remarkably induce nephrotoxicity 60 . It has been estimated that around 41% of mpox patients has a concurrent HIV infection in a cohort study 42 .…”

Section: Renal Complicationsmentioning

confidence: 99%

“…It has been estimated that around 41% of mpox patients has a concurrent HIV infection in a cohort study 42 . Finally, secondary bacterial infections and sepsis complicating soft tissues injuries and mpox‐related ulcers might also be a potential etiology for AKI 60 . In this context, Mitjà et al 23 .…”

Section: Renal Complicationsmentioning

confidence: 99%

“…For instance, assessment of urinary phosphate and uric acid can predict proximal tubule dysfunction by detecting hypophosphatemia with hyperphosphaturia and hypouricemia with hyperuricosuria. Assessment of urinary β 2 ‐microglobulin might also be useful (dysfunction: 0.30 mg/L) 60 …”

Section: Renal Complicationsmentioning

confidence: 99%

“…The medication is usually administered by HIV patients and can remarkably induce nephrotoxicity. 60 It has been estimated that around 41% of mpox patients has a concurrent HIV infection in a cohort study. 42 Finally, secondary bacterial infections and sepsis complicating soft tissues injuries and mpox-related ulcers might also be a potential etiology for AKI.…”

Section: F I G U R E 3 Interventions For Mpox Patients and Mechanisms...mentioning

confidence: 99%

“…42 Finally, secondary bacterial infections and sepsis complicating soft tissues injuries and mpox-related ulcers might also be a potential etiology for AKI. 60 In this context, Mitjà et al 23 showed that multiorgan failure and septic shock were the commonest cause of death in their mpox population (N = 20/27).…”

Section: F I G U R E 3 Interventions For Mpox Patients and Mechanisms...mentioning

confidence: 99%

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Mpox impact on different organ systems: Complications, mechanisms, and management

Reda

Dhama

2023

Reviews in Medical Virology

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Mpox (previously known as monkeypox) continues to raise concerns since many cases are still being recorded globally. Various reports have shown changing epidemiology of the disease, together with different atypical clinical characteristics of affected patients. The condition has reportedly been self-limited since most patients do not usually require hospitalisation. However, recent reports showed that some patients might suffer from related complications and require hospitalisation.Different systems were reportedly affected, including cardiac, neurological, respiratory, and renal events. In the present literature review, we aim to review these complications, discuss their potential mechanisms, and provide insight into the currently recommended diagnostic and management practices.

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Section: Renal Complicationsmentioning

confidence: 99%

Section: Renal Complicationsmentioning

confidence: 99%

Section: Renal Complicationsmentioning

confidence: 99%

Section: F I G U R E 3 Interventions For Mpox Patients and Mechanisms...mentioning

confidence: 99%

Section: F I G U R E 3 Interventions For Mpox Patients and Mechanisms...mentioning

confidence: 99%

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Mpox impact on different organ systems: Complications, mechanisms, and management

Reda

Dhama

2023

Reviews in Medical Virology

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Mpox and Surgery: Protocols, Precautions, and Recommendations

Kamaratos-Sevdalis,

Kourampi,

Ozturk

et al. 2024

Microorganisms

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Mpox, also known as Monkeypox, is an infectious disease known to spread via direct contact and fomites, which poses a significant contagion risk in surgical settings and may increase the challenges already posed by COVID-19. Within the three years following the outbreak of Mpox, we conducted a review of the impact of Mpox on surgical practice. We searched Pubmed/Medline and Scopus, focusing on original studies and case reports in English or German. Our search terms included “Mpox”, “Monkeypox”, and “Surgery”. Out of 60 clinical or epidemiological studies, as well as expert opinions, brief reports, and pertinent literature reviews, eight were included after full-text assessment. We also incorporated two pertinent literature reviews, including a total of 10 papers, in this analysis. The main topics addressed by the literature are 1. manifestations of Mpox for surgical consideration or urgent management, for which it is important to consider whether a surgical approach is needed to address long-term Mpox-related lesions and 2. infection control in surgical settings, especially considering its impact on elective surgery and the well-being of healthcare workers. Mpox could affect surgical services and access to operating theaters. Unlike COVID-19, Mpox, compared to initial concerns, has not substantially compromised surgical delivery. However, limited reports exist on the surgical impact of Mpox. It is crucial to involve surgeons in Mpox diagnosis, educate surgical practitioners on its mimicry of common surgical conditions, enhance infection control during surgery, and ensure access to corrective surgery as a means of tackling the stigmatization associated with Mpox and sexually transmitted diseases in general.

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Monkeypox-Associated Acute Kidney Injury and Foreseeable Impacts on Nephrology and Kidney Transplantation Services

Cited by 2 publications

References 9 publications

Mpox impact on different organ systems: Complications, mechanisms, and management

Mpox impact on different organ systems: Complications, mechanisms, and management

Mpox and Surgery: Protocols, Precautions, and Recommendations

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