Monkeypox outbreak in the Tel Aviv District, Israel, 2022

Savion, Michal; Nuss, Naama; Amitai, Ziva; Salama, Matanelle

doi:10.1016/j.ijid.2022.12.023

Cited by 6 publications

(1 citation statement)

References 3 publications

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“…Province-wide mpox incidence was assumed to reflect transmission in each city given that the majority of the cases were reported from these cities. 5–7 Briefly, we used publicly available data on reported mpox cases 6 to estimate this R 0 using the formula R 0 =: 1 + D Λ, where the duration of infectiousness D is assumed to be 17.3 days, 35–38 and the epidemic growth rate Λ was estimated from the slope of the log cumulative cases over time. We used the first 50 days after the first case in each province, which corresponded to the period of initial exponential growth.…”

Section: Methodsmentioning

confidence: 99%

Characteristics of the sexual networks of gay, bisexual, and other men who have sex with men in Montréal, Toronto, and Vancouver: implications for the transmission and control of mpox in Canada

Xiu,

Anato,

Cox

et al. 2023

Preprint

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Background: The 2022-2023 global mpox outbreak disproportionately affected gay, bisexual, and other men who have sex with men (GBM). In Canada, >70% of cases thus far have been among GBM in Montréal, Toronto, and Vancouver. We examined how the distributions of sexual partners 1) varied by city and over time related to the COVID-19 pandemic and 2) were associated with mpox transmission. Methods: TheEngage Cohort Study(2017-2023) recruited GBM via respondent-driven sampling in Montréal, Toronto, and Vancouver (n=2,449). We compared numbers of sexual partners in the past 6 months across cities and three time periods: pre-COVID-19 pandemic (2017-2019), pandemic (2020-2021), and post-restrictions (2021-2023). We modeled the distribution of sexual partner numbers using Bayesian negative binomial regressions and post-stratification, adjusting for sampling design and attrition. We estimated the basic reproduction number (R0), secondary attack rate (SAR), and cumulative incidence proportion of mpox using the fitted distributions and case timeseries. Results: The pre-COVID-19 pandemic distribution of sexual partner numbers was similar across cities: participants' mean number of partners was 10.3 (95%CrI: 9.3-11.3) in Montréal, 12.8 (11.1-14.7) in Toronto, and 10.6 (9.41-11.9) in Vancouver. Partner numbers decreased during the pandemic in all cities. Post-restrictions, sexual activity increased but remained well below pre-pandemic levels. Based on reported cases and post-restrictions distributions, the estimatedR0(2.4-2.6) and cumulative incidences (0.6-0.9%) were similar across cities. The estimated average SAR across cities was 79%. Conclusion: GBM sexual activity after restrictions were lifted remained below pre-pandemic levels. Comparable sexual partner distributions across cities may explain similarities in mpoxR0and cumulative incidence across cities. Public health authorities should consider the risk of mpox resurgence for future vaccination and surveillance strategies as sexual activity is expected to recover.

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Section: Methodsmentioning

confidence: 99%