Monoclonal antibodies to small-cell carcinoma of the human lung

Goncharskaya, M. A.; Rutkevich, N. M.; Tonevitskii, A. G.; Орел, Н Ф; Vasil’ev, A. V.; Переводчикова, Н И; Mechetner, Eugene

doi:10.1007/bf00840610

Bull Exp Biol Med

1991

DOI: 10.1007/bf00840610

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Monoclonal antibodies to small-cell carcinoma of the human lung

M. A. Goncharskaya¹,

N. M. Rutkevich²,

A. G. Tonevitskii³

et al.

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1996

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“…We obtained a panel of MAb to surface antigens of SPC cells [1]. This study was aimed at investigating the possibility of using these MAb for in vitro immunodiagnosis of metastases of SPC to the bone marrow by indirect immunofluorescence.…”

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confidence: 99%

In vitro detection of metastases of small-cell pulmonary carcinoma to the bone marrow using monoclonal antibodies

et al. 1996

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A panel of five monoclonal antibodies to surface antigens of small-cell pulmonary carcinoma was used for immunodiagnosis of metastases to the bone marrow in vitro in patients with small-cell carcinoma of the lungs. Standard cytomorphological diagnosis revealed metastases to the bone marrow in 6 out of 58 patients (10.3%). Using monoclonal antibodies, positive cells were detected in 12 (20.6%) patients, the tumor nature of the positive cells being undoubted in 7 preparations (12.6%). Five out of 6 cytologically positive cases were confirmed.

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In vitro detection of metastases of small-cell pulmonary carcinoma to the bone marrow using monoclonal antibodies

et al. 1996

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Monoclonal antibodies to small-cell carcinoma of the human lung

Cited by 1 publication

References 8 publications

In vitro detection of metastases of small-cell pulmonary carcinoma to the bone marrow using monoclonal antibodies

In vitro detection of metastases of small-cell pulmonary carcinoma to the bone marrow using monoclonal antibodies

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