2023
DOI: 10.3389/fimmu.2023.1124894
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Monocyte subpopulations display disease-specific miRNA signatures depending on the subform of Spondyloarthropathy

Abstract: Spondyloarthropathies (SpA) are a family of rheumatic disorders that could be divided into axial (axSpA) and peripheral (perSpA) sub-forms depending on the disease clinical presentation. The chronic inflammation is believed to be driven by innate immune cells such as monocytes, rather than self-reactive cells of adaptive immune system. The aim of the study was to investigate the micro-RNA (miRNA) profiles in monocyte subpopulations (classical, intermediate and non-classical subpopulations) acquired from SpA pa… Show more

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