Monodisperse CuPd alloy nanoparticles as efficient and reusable catalyst for the C (sp²)–H bond activation

Abstract

Metal‐catalyzed selective activation of C–H bonds is very important for the construction of a variety of biologically active molecules. Supported alloy nanoparticles are of great interest in various catalytic applications due to the synergistic effects between different metals. Here, well‐dispersed CuPd alloy nanoparticles supported on reduced graphene oxide (rGO) were synthesized and found to be highly efficient and recyclable catalyst for the chelation‐assisted C (sp2)–H bond activation. Aromatic ketones or esters were synthesized via the cross‐dehydrogenative coupling (CDC) reaction between 2‐arylpyridines and alcohols or acids. Moreover, the catalyst was recovered and used for five times without significantly losing activity.

Supported Metal Nanoparticles Assisted Catalysis: A Broad Concept in Functionalization of Ubiquitous C−H Bonds

“…Earlier reported protocol (Section 4.1.3) by Huang et al. (2021) expended for Cu/Pd@rGo catalysed C−H acetoxylation by activation of C−H bond [157] . Various nitrogen‐based directing groups such as pyridine pyrazole, benzothiazole, and pyrimidine worked well, affording the acetoxylation of C−H bond to give desired products in moderate to good yields (Scheme 39A).…”

“…Recently, Huang et al. (2021), reported an example of a highly efficient and recyclable supported Cu/Pd bimetallic NPs catalysed chelation assisted C(sp 2 )−H bond activation to afford cross‐dehydrogenative coupling reactions [157] . The different alloy catalysts have been prepared by varying composition of Cu and Pd ratio and monodispersing onto reduced graphene oxide (rGO) (so‐called Cu/Pd@rGO).…”

Electro- and photoactivation of silver–iron oxide particles as magnetically recyclable catalysts for cross-coupling reactions

“…32,33 Very recently, Agcoated Fe 3 O 4 has been used to catalyze the oxidation and condensation of benzylic alcohols into dihydrochalcones. 57 Here we describe the synthesis of magnetically responsive silver-iron oxide (SIO) particles and their use as heterogeneous redox catalysts for direct C(sp 2 )-H heteroarylation, a frequently used method for the cross coupling of heterocycles and aryldiazonium ions in the synthesis of pharmaceutical intermediates. 34,35 These materials differ from previous Ag/Fe x O y catalysts in several respects: (i) they are inverse catalysts with iron oxide serving as the minor species; (ii) they are strongly plasmon-resonant, similar to other types of colloidal Ag; and (iii) they can be prepared under green chemistry conditions in aqueous solutions without amphiphilic surfactants.…”

“…32,33 Very recently, Ag-coated Fe 3 O 4 has been used to catalyze the oxidation and condensation of benzylic alcohols into dihydrochalcones. 57…”

Catalytic dehydrogenation of natural terpenes via CuPd alloy nanoparticles generated on mesoporous graphitic carbon nitride

“…Heterogeneous catalysts are vital for most of the chemical and energy industries [1] due to their distinct advantages including facile preparation and high reusability compared to homogeneous catalysts. [2,3] As heterogeneous catalysts show catalytic activity through their surface atoms, increasing of their surface-to-volume ratio via reducing their particle size is one of the most efficient strategies for increasing their catalytic activities. [4] However, the catalytic activity is not always enhanced by reducing the size of the nanoparticles.…”