We discuss a number of open problems about mapping class groups of surfaces. In particular, we discuss problems related to linearity, congruence subgroups, cohomology, pseudo-Anosov stretch factors, Torelli subgroups, and normal subgroups.Beginning with the work of Max Dehn a century ago, the subject of mapping class groups has become a central topic in mathematics. It enjoys deep and varied connections to many other subjects, such as lowdimensional topology, geometric group theory, dynamics, Teichmüller theory, algebraic geometry, and number theory. The number of papers on mapping class groups recorded on MathSciNet in the last six decades has grown from 205 to 386 to 525 to 791 to 1,121 to 1,390. The subject seems to enjoy an endless supply of beautiful ideas, pictures, and theorems. arXiv:1806.08773v1 [math.GT] 22 Jun 2018 Question 1.1. Is Mod(S g ) linear?Dehn proved that Mod(T 2 ), the mapping class group of the torus, is isomorphic to SL 2 (Z) ⊆ GL 2 (C). In the case g = 2 the Birman-Hilden theory [108] gives a short exact sequence:where ι is the hyperelliptic involution of S 2 . The group Mod(S 0,6 ) is closely related to the braid group on 5 strands. As such, Bigelow-Budney and Korkmaz were able to prove that Mod(S 2 ) is linear, using the theorem of Krammer and Bigelow that braid groups are linear [14,90]. For g ≥ 3, Question 1.1 is wide open.Linearity of the braid group. One might be tempted to think that Mod(S g ) is not linear, because if it were then we would already have stumbled across the representation. On the other hand, we should draw inspiration from the case of the braid group. The Burau representation