We discuss some physical consequences of the resurgent structure of Painlevé equations and their related conformal block expansions. The resurgent structure of Painlevé equations is particularly transparent when expressed in terms of physical conformal block expansions of the associated tau functions. Resurgence produces an intricate network of inter-relations; some between expansions around different critical points, others between expansions around different instanton sectors of the expansions about the same critical point, and others between different non-perturbative sectors of associated spectral problems, via the Bethe-gauge and Painlevé-gauge correspondences. Resurgence relations exist both for convergent and divergent expansions, and can be interpreted in terms of the physics of phase transitions. These general features are illustrated with three physical examples: correlators of the 2d Ising model, the partition function of the Gross-Witten-Wadia matrix model, and the full counting statistics of one dimensional fermions, associated with Painlevé VI, Painlevé III and Painlevé V, respectively.