Monolithically integrated InGaAsP multiple quantum well tunable laser diode for integrated optic surface plasmon resonance sensing

Optoelectronics and Optical Bio-Sensors

“…Currently, several manufacturing are fabricating SPR devices. Moreover, nowadays, the SPR-based biosensor is the dominant method of biosensing [56,57].…”

“…To obtain a sensogram, the shift of reflectivity, wavelengths or angle are measure against time. In all configuration, label-free, direct and real-time changes of refractive index is enabled by the phenomenon of SPR at the surface of sensor, in which it is proportional to the concentration of the biomolecule as shown in Figure 8 [58].…”

“…Nevertheless, the current implemented and commercial SPR sensors are comparatively massive size systems and have low throughput, in which they limit their applications range. Hence, higher throughputs are needed with additional disposable and compact SPR system, even though that some of their problems have solved partially [56,[61][62][63][64].…”

“…This section and all the fabrication and results have been achieved previously by MQW Group at UCF [56][57][58][59]64]. In this work, a sensor head of optical surface plasmon resonance (SPR) has illustrated in this work.…”

“…Therefore, based on these measurements, the sensor devices sensitivity was specified to be S = 232 nm.RIU-1. In this section, we demonstrate that the device can be integrated completely with a photodetection unit, a wavelength tunable light source and a liquid delivery system through microfluidic channels to make it an extremely compact unit [56][57][58][59]64].…”