Mononuclear and coordination polymer of silver(I) complexes: design, synthesis, and crystal structure analysis

Rahazat, Nur R.A.; Haque, Rosenani A.; Ng, Seik Weng; Razali, Mohd. R.

doi:10.1080/00958972.2015.1014348

Cited by 11 publications

(2 citation statements)

References 31 publications

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“…The average bond angles around the silver(I) centre varied from 104.63° to 105.98°, consistent with a distorted tetrahedral geometry. Further, the Ag−O and Ag−P bond distances are consistent with related tetrahedral silver(I) complexes [20d–g,24] …”

Section: Resultssupporting

confidence: 70%

Anti‐Breast Cancer Stem Cell Properties of Silver(I)‐Non‐Steroidal Anti‐Inflammatory Drug Complexes

Singh,

Johnson

et al. 2024

Eur J Inorg Chem

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The synthesis and characterisation of a series of silver(I) complexes (1‐7) containing non‐steroidal anti‐inflammatory drugs (NSAIDs) and triphenylphosphine ligands is reported. The diclofenac‐containing silver(I) complex 1 exhibits micromolar potency towards bulk breast cancer cells and breast cancer stem cells (CSCs) cultured in monolayers. Notably, the silver(I) complex 1 displays up to 9.4‐fold higher potency towards three‐dimensional mammospheres than cisplatin (a clinically used anticancer metallodrug) and salinomycin (a breast‐CSC active small molecule). Mechanistic studies show that the silver(I) complex 1 readily interacts with thiol‐containing biomolecules in solution and elevates intracellular reactive oxygen species levels in breast CSCs. Interestingly the silver(I) complex 1 does not perturb cyclooxygenase‐2 (COX‐2) expression in breast CSCs and its cytotoxicity is unaffected in the presence of prostaglandin E2, implicative of a COX‐2 independent mechanism of action.

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Section: Resultssupporting

confidence: 70%

Anti‐Breast Cancer Stem Cell Properties of Silver(I)‐Non‐Steroidal Anti‐Inflammatory Drug Complexes

Singh,

Johnson

et al. 2024

Eur J Inorg Chem

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“…As continuation to our previous work [14,15], an attempt to synthesize copper(I) complexes containing picolinate, 2pyCOO − was unsuccessful, instead the formation of copper(II) species in a heterobimetallic 2-D coordination polymer namely, [Na2(Cu2I2(2pyCOO)4)(H2O)4]n (1) was observed. The oxidation of copper(I) to copper(II) is due to the exposure to air during experimental work.…”

Section: Resultsmentioning

confidence: 99%

A Heterobimetallic 2-D Coordination Polymer [Na2(Cu2I2(2pyCOO)4)(H2O)4]n (2pyCOO−=picolinate) within a 3-D Supramolecular Architecture

2016

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Abstract:A heterobimetallic 2-D coordination polymer, [Na 2 (Cu 2 I 2 (2pyCOO) 4 )(H 2 O) 4 ] n (1) (2pyCOO=picolinate) was synthesized and characterized. The complex was also structurally characterized using single X-ray diffraction studies that revealed the complex 1 having a vertex symbol of 4.8 2 which corresponds to fes topology. Together with hydrogen bonds and interdigitating π···π interactions, these thus facilitate the formation of 3-D supramolecular network. The nitrogen gas absorption amount of 1 at 77 K shows a small volume of N 2 sorption isotherm with a small Langmuir and a Brunauer-Emmett-Teller (BET) surface area indicating that the heterobimetallic 3-D supramolecular of 1 exhibits a very weak ability of adsorbing gas.

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Anion Directed Self‐Assembly of One‐Dimensional and Two‐Dimensional Coordination Polymers Containing Bridging Diphosphine Ligands

Shawkataly

Sani

Rosli

et al. 2016

Zeitschrift anorg allge chemie

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The reactions of 1,2-bis(diphenylphosphanyl)ethane (dppe) with different silver(I) salts facilitated the formation of 1D and 2D coordination polymers, [Ag(dppe)(OAc)] n ·nH 2 O (1) and [Ag 2 (dppe) 1.5 (NO 3 ) 2 ] n (2), respectively. The complexes were characterized by elemental analysis, ATR-IR spectroscopy, 1 H NMR, 13 C NMR, and 31 P NMR spectroscopy, and single-crystal X-ray diffraction. Structural analysis revealed that complex 1 exhibits a 1D infinite wavy

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Mononuclear and coordination polymer of silver(I) complexes: design, synthesis, and crystal structure analysis

Cited by 11 publications

References 31 publications

Anti‐Breast Cancer Stem Cell Properties of Silver(I)‐Non‐Steroidal Anti‐Inflammatory Drug Complexes

Anti‐Breast Cancer Stem Cell Properties of Silver(I)‐Non‐Steroidal Anti‐Inflammatory Drug Complexes

A Heterobimetallic 2-D Coordination Polymer [Na2(Cu2I2(2pyCOO)4)(H2O)4]n (2pyCOO−=picolinate) within a 3-D Supramolecular Architecture

Anion Directed Self‐Assembly of One‐Dimensional and Two‐Dimensional Coordination Polymers Containing Bridging Diphosphine Ligands

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