Mononuclear metal complexes with ciprofloxacin: Synthesis, characterization and DNA-binding properties

Interactions of Vitamin K3 with Herring-Sperm DNA Using Spectroscopy and Electrochemistry

“…This positive shift of the E 1/2 value suggests the existence of intercalation between vitamin K 3 and DNA. 27,28 The analysis results of cyclic voltammetry agree with the results of the competitive experiment. Combined with the Scatchard method, we can arrive at the conclusion that the interaction mode between vitamin K 3 and herring-sperm DNA is a mixed mode that includes intercalation and electrostatic binding.…”

Re(I) tricarbonyl complex of 1,10-phenanthroline-5,6-dione: DNA binding, cytotoxicity, anti-inflammatory and anti-coagulant effects towards platelet activating factor

“…3 shows the cyclic voltammograms of the complex 1 (100 μM) at the absence and presence of CT-DNA (200 μΜ). After addition of DNA to the complex no new redox peaks appeared, but the current intensity of all the peaks decreased, suggesting the existence of an interaction between 1 and CT-DNA, and can be explained in terms of an equilibrium mixture of free and DNA-bound complex to the electrode surface [52]. From Fig.…”

Investigation of DNA binding mechanism, photoinduced cleavage activity, electrochemical properties and biological functions of mixed ligand copper(II) complexes with benzimidazole derivatives: synthesis and spectral characterization

“…For increasing amounts of CT DNA, the cathodic potential Epc shows a positive shift (ΔEpc = +0.013 V for 1, ΔEpc = +0.018 V for 2, ΔEpc = +0.020 V for 3 and ΔEpc = +0.021 V for 4) while the anodic potential Epa shifts to more negative values [ΔEpa = −0.057 V for 1 ( Figure S3A, supplementary material), ΔEpa = -0.051 V for 2, ΔEpa = −0.007 V for 3 for Cu(III)/Cu(II) redox couple], the cathodic potential Epc shows a positive shift (ΔEpc = +0.017 V for 1, ΔEpc = +0.030 V for 2, ΔEpc = +0.037 V for 3 and ΔEpc = +0.050V for 4) while the anodic potential Epa shifts to negative values [ΔEpa = −0.022V for 1, ΔEpa = -0.064V for 2, ΔEpa = −0.014V for 3 and ΔEpa = −0.039V for 4 ( Figure S3 B, supplementary material)] for Cu(II)/Cu(I) redox couple respectively. These shifts of the potentials show that complexes 1-4 can bind to DNA by both intercalation and electrostatic interaction 25 .…”