Monosomy of chromosome 8 could be considered as a primary preneoplastic event in breast cancer: A preliminary study

Abstract

Abstract. This pilot study analyzed and compared the presence of chromosome 8 aneusomy in Mexican women with breast cancer and adjacent, intraductal, proliferative lesions.

Correlation of morphological markers of chromosomal instability in fine needle aspiration cytology with grade of breast cancer

“…Studies of breast cancer karyotypes have demonstrated that this type of cancer frequently has the structural genomic aberrations as seen in other forms of human cancer, including aneuploidy. [4][5][6][7] Furthermore, several previous studies have shown variability of chromosome numbers from cell to cell within a given breast cancer, [8][9][10][11] suggesting that breast cancers also have chromosomal instability.…”