Monosporosis vs. Allescheriasis

Arnett, Jerome C.; Buechner, Howard A.; Hatch, Hurst B.

doi:10.1378/chest.68.1.129a

Cited by 3 publications

(3 citation statements)

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“…Pseudallescherioma of the lung is the extreme consequence of intercavitary colonization, where the mass of fungus reaches sufficient size to be visible radiologically. 3,9,14,22,44,69,87,109,111,119,121,123,125,152,154 Radiographs of the pseudallescheriomas show the presence of a solid, round or oval mass with soft tissue opacity within a lung cavity.…”

Section: Clinical Presentationsmentioning

confidence: 99%

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Clinical characteristics and epidemiology of pulmonary pseudallescheriasis

Kantarcıoğlu

Hoog

Guarro

2012

Revista Iberoamericana de Micología

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The main clinical manifestations of the 189 cases of pulmonary pseudallescheriasis reviewed were pneumonia (89), followed by fungus ball (26), and chest abscess (18). Some patients had more than one type of invasive pulmonary manifestations. Among patients with pneumonia, several cases of pneumonia associated with near-drowning (10/89, 11.2%) have also been reported in immunocompetent hosts. Major underlying conditions for non-invasive pulmonary infection were preexisting lung cavities and medical immunosuppression for invasive pulmonary infection. Saprobic airway colonization was mostly seen in patients with mucosal dysfunction, i.e. patients with cystic fibrosis. The mortality rate was closely related to the infection type, being 26.8% in non-invasive type (fungus balls) and 57.2% in invasive type.

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Section: Clinical Presentationsmentioning

confidence: 99%

“…Three general reviews, on a range of PSC infections 29,52 and central nervous system (CNS) infections, 68 have recently been published. In addition, a few more, shorter, reviews each covering a small number of previous cases 6,9,14,82,109,113,115 have also been published. The clinical spectrum of the disease associated with PSC was examined by Rippon, in 1980.…”

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confidence: 99%

Clinical characteristics and epidemiology of pulmonary pseudallescheriasis

Kantarcıoğlu

Hoog

Guarro

2012

Revista Iberoamericana de Micología

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“…Other authors prefer to refer to the two stages exactly as they were isolated as if they were two distinct organisms. When two supposedly different fungi are subsequently found to be sexual and asexual forms of the same fungus, the conventional nomenclature is to name the disease after the sexual form [17,18]. There are no known clinically significant epidemiologic features, host risk factors or clinical manifestations that differentiate P. boydii from S. apiospermum.…”

Section: Nomenclaturementioning

confidence: 99%

Pseudallescheriasis in the 21st century

O’Bryan

2005

Expert Review of Anti-infective Therapy

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Since its discovery as an agent of mycetoma nearly a century ago, Pseudallescheria boydii with its asexual (synanamorphic) form, Scedosporium apiospermum, is now recognized as an important emerging opportunistic pathogen causing invasive mycosis in immunocompromised patients. The clinical spectrum of pseudallescheriasis is wide. Invasive disease of the lung, CNS and dissemination are serious manifestations in immunocompromised patients. This organism responds poorly to amphotericin B, and its histopathologic resemblance to aspergillosis often results in a delay in diagnosis. In vitro data, animal models and accumulating clinical experience support the use of voriconazole as a primary treatment for pseudallescheriasis. This paper reviews the microbiology, ecology, epidemiologic trends, clinical manifestations and current treatment options of pseudallescheriasis.

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Systemic pseudallescheriasis in a patient with acute myelocytic leukemia

et al. 1985

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Presented is a case of widely disseminated systemic pseudallescheriasis in a 41 year old male with acute myelocytic leukemia. The immediate cause of death appeared to be due to an extensive invasion of the lungs which showed massive intra-alveolar hemorrhages, congestion, mycotic thrombi, and multiple fungal lesions in all lobes. Pseudallescheria boydii was diagnosed histopathologically by virtue of its characteristic conidia present in miliary lesions throughout a wide range of host's tissues, including the brain and the thyroid. Three antemortem blood specimens cultured during the patient's final hospital stay were positive for the fungus. It was concluded the fungemia was responsible for the rapid and widespread dispersion of P. boydii in this debilitated patient who was granulocytopenic and immunosuppressed.

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Monosporosis vs. Allescheriasis

Cited by 3 publications

References 1 publication

Clinical characteristics and epidemiology of pulmonary pseudallescheriasis

Clinical characteristics and epidemiology of pulmonary pseudallescheriasis

Pseudallescheriasis in the 21st century

Systemic pseudallescheriasis in a patient with acute myelocytic leukemia

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