Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature

Abstract

Fibrous dysplasia (FD) is a progressive systemic bone tumour of young and it can be seen on cranial bones. FD is divided into three types according to radiological features. The second most common subtype is polyostotic subtype. With this article, we aimed to review and present clinical features, radiological examination, differential diagnosis and treatment management of a case of solitary monostotic fibrous dysplasia of occipital bone. 15 years old female patient admitted to our hospital for a bump and in the back of his head that she noticed 1 month ago. Her physical and neurological examination was normal. On cranial CT examination we detected a bony defect. Her gadolinium enhanced cranial MRI revealed bony defect along with massive gadolinium enhancement in adjacent tissue. On histopathologic examination; PANCK, CD68, CD1a were found negative and CD45, S-100, Vimentine were found positive. Ki-67 was 4,8%. In conclusion, fibrous dysplasia is a progressive bone disease of the young patients. Despite its resemblance to a benign lesion by not being symptomatic it can progress and cause severe bony defects and skin lesions. Total surgical resection is necessary and sufficient for total treatment.

Fibrous dysplasia of occipital and temporal bone. A case report

“…In our case the patient presented with minimal symptoms: local enlargement and slight tenderness. So did the 19-year-old patient of Itshayek et al [11], who had concomitant aneurysmal bone cyst, the 15-year-old girl of Basaran et al [12] and the single patient with occipital bone involvement of the Gupta et al . case series [13].…”

Giant monostotic osteofibrous dysplasia of the ilium: A case report and review of literature

“…At present, the major treatment strategies for OFD are conservative treatment and surgical treatment[ 21 ]. Although it is a benign lesion with no symptoms, it is progressive and may lead to severe defects and lesions in bone and skin[ 2 ]. The surgical methods for OFD mainly include focus curettage and bone grafting combined with or without external fixation[ 22 - 25 ].…”

“…Osteofibrous dysplasia (OFD) is a developmental skeletal disorder and is characterized by substitution of normal bone with benign cellular fibrous connective tissue[ 1 ]. Currently, OFD can be classified as monostotic, polyostotic and McCune Albright syndrome[ 2 ]. Most cases of monostotic lesions present no significant symptoms and are often found incidentally on radiography taken for other symptoms[ 3 ].…”