Monoterpene and lignan glycosides in the leaves of Crataegus pinnatifida

Chemical constituents of Miliusa balansae leaves and inhibition of nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells

“…NMR data of 1 were similar to those of (3S,5R,6R,7E,9R)-3, 6-epoxy-7-megastigmene-5,9-diol-9-O-b-D-glucopyranoside, 16 except for the replacement of a carbonyl at C-9, hydroxyl group at C-2, and a glucose moiety attached to C-5. The structure of 1 was further confirmed by HMQC and HMBC experiments.…”

“…The methyl proton H-11 (d H 1.49) observed HMBC correlations with C-1 (d C 51.1)/C-2 (d C 85.1)/C-6 (d C 93.1)/C-12 (d C 23.9) and cross-peaks with methine H-3 (d H 4.16) with C-1 (d C 51.1)/C-2 (d C 85.1)/C-4 (d C 43.7)/C-6 (d C 93.1), confirming the location of a hydroxy group at C-2 and authenticating the presence of a 3,6-epoxy bridge. 16 The presence of a carbonyl group at C-9 was confirmed using HMBC correlations between H-10 (d H 2.33) and C-9 (d C 201.1)/C-8 (d C 131.6); H-7 (d H 7.02) and C-6 (d C 93.1)/C-8 (d C 131.6)/C-9 (d C 201.1). Moreover, a sugar moiety was located at C-5, which was also supported by HMBC correlations between the anomeric proton H-1 0 (d H 4.44) and C-5 (d C 88.5).…”

Crataegus pinnatifida Bge. 山楂 (Shanzha, Hawthorn Fruit)

“…In addition, the phytochemical studies on these materials also revealed many active phenylpropanoids in the seeds [7], monoterpenes, sesquiterpene, lignans, sesquilignan, hexane and their glycosides in the leaves [3,[8][9][10] of C. pinnatifida.…”

“…Triterpenoidal compounds isolated from Shanzha include ursolic acid (7), corosolic acid (8), oleanolic acid (9), maslinic acid (crataegolic acid, 10) etc. [12].…”

Crataegus pinnatifida: Chemical Constituents, Pharmacology, and Potential Applications

“…In 2009, (88) was isolated from the leaves of C. pinnatifida [39]. Later, (7S,8R)- (96) were also isolated from the leaves of C. pinnatifida in 2010 [36]. Recently, some novel neolignans were isolated from the seeds of C. pinnatifida, including pinnatifidanin C I-VIII, pinnatifidanin B I-IX (97-112) [40][41][42] (Figure 8).…”