Monoterpenes and flavones from the leaves of Crataegus pinnatifida with anticoagulant activities

Li, Lingzhi; Gao, Pin‐Yi; Song, Shao‐Jiang; Yuan, Yan-Qiang; Liu, Chun‐Ting; Huang, Xiao‐Xiao; Liu, Qingbo

doi:10.1016/j.jff.2014.11.012

Cited by 36 publications

(16 citation statements)

References 29 publications

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“…Aqueous solutions of citric acid and methanol were compared for C. monogyna fruit; it was found that the former was favorable in terms of total yield, TPC and ascorbic acid, while DPPH • and ABTS •+ scavenging capacity was not dependent on the solvent (Pliszka et al, 2016). Hawthorn seeds, as a byproduct of manufacturing hawthorn juice and jam, were evaluated as a potential new and cheap source of antioxidants and inflammation inhibitor (Huang et al, 2015).…”

Section: Composition and Health Effects Of Phenolic Compoundsmentioning

confidence: 99%

Phytochemical composition and bioactivities of hawthorn ( Crataegus spp.): review of recent research advances

Venskutonis¹

2018

Journal of Food Bioactives

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Hawthorn (Crataegus spp.) is one of the most famous plants which has been used as natural medicine and nutraceutical. Its phytochemical composition, bioactive compounds and health benefits have been intensively studied and hawthorn preparations may be recognized as classical natural products for cardiovascular health. Polyphenolic compounds of different hawthorn anatomical parts as well as their extracts have been the focus of a majority of these studies, although various other classes of natural health promoting constituents have also been isolated, identified and characterized. Regardless, numerous published reports have particularly focused on the activity mechanisms which are very important for supporting various health benefits. This review summarizes the most recent studies on hawthorn, mainly published since 2015. Search of different databases indicates that approximately 200 publications, which are relevant to phytochemistry and health benefits of Crataegus spp., have appeared since then, most of them have not been included in the existing reviews.

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Section: Composition and Health Effects Of Phenolic Compoundsmentioning

confidence: 99%

Phytochemical composition and bioactivities of hawthorn ( Crataegus spp.): review of recent research advances

Venskutonis¹

2018

Journal of Food Bioactives

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“…A large number of plants in this genus have been used in folk medicine and food owing to its various pharmacological activities. Accumulative studies indicate that Crataegus plants produce massive biologically active substances including phenylpropanoids, flavonoids, monoterpenoids, sesquiterpenoids, triterpenoids, phenolic acids, and so on, some of which display remarkable biological activities.…”

Section: Introductionmentioning

confidence: 99%

New Constituents from the Low Polar Fraction of the Fruits of Crataegus dahurica and Their Anti‐Inflammatory Activity in RAW264.7 Cells

Wang

Gao

Chen

et al. 2020

Chemistry & Biodiversity

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The fruit of Crataegus dahurica Koehne was used to treat the disease of infantile indigestion and dyspepsia as an ethnic medicine and food. As a continuous work on finding the active constituents from the edible herbs, four new biphenyl derivatives (1–4), together with two known compounds (5 and 6), were obtained from the petroleum ether fraction of the fruits of C. dahurica. Their structures were determined by the extensive 1D and 2D NMR spectra and HR‐MS spectrometry. Furthermore, the anti‐inflammatory activities of all the isolated compounds were investigated, in which compound 4 showed moderately inhibitory effects on NO production in RAW264.7 cells without inducing cytotoxicity.

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“…Hawthorns grow abundantly in regions with high light intensity, alongside rivers or lakes or in anthropogenic areas. Flowers are insect-pollinated, and small, fleshy fruits containing 1-5 seeds [42,46] are an important source of food, not only for different kinds of animals but also for humans [47,48]. Seeds are produced either by allogamy, which is common in diploid hawthorns, when self-fertilisation is prevented by gametophytic self-incompatibility [18,49], or by autogamy and apomixis common in polyploids [50].…”

Section: Introductionmentioning

confidence: 99%

Breeding Systems in Diploid and Polyploid Hawthorns (Crataegus): Evidence from Experimental Pollinations of C. monogyna, C. subsphaerica, and Natural Hybrids

Vašková

Kolarčik

2019

Forests

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Background and Objectives: Polyploidisation and frequent hybridisation play an important role in speciation processes and evolutionary history and have a large impact on reproductive systems in the genus Crataegus. Reproductive modes in selected diploid and polyploid taxa in eastern Slovakia were investigated and analysed for the first time. Materials and Methods: Diploid, triploid, and tetraploid hawthorns were tested for self-pollination, self-compatibility, and self-fertilisation. Pollination experiments were performed within and between diploid and triploid species to determine the possibilities and directions of pollen transfer under natural conditions. Seeds from crossing experiments and open pollinations were analysed using the flow cytometric seed screen method. Results: These experiments demonstrated that sexual reproduction, cross-pollination, and self-incompatibility are typical of the diploid species Crataegus monogyna and C. kyrtostyla. Seeds produced by self-fertile tetraploid C. subsphaerica were derived from both meiotically reduced and unreduced megagametophytes. Conclusions: Experimental results concerning triploid C. subsphaerica and C. laevigata × C. subsphaerica are ambiguous but suggest that seeds are almost exclusively created through apomixis, although a few sexually generated seeds were observed. In the genus Crataegus, pseudogamy is a common feature of polyploid taxa, as in all cases pollination is essential for regular seed development. Research Highlights: We suggest that all studied Crataegus taxa produce reduced pollen irrespective of ploidy level. Moreover, we emphasise that triploids produce apparently aneuploid pollen grains as a result of irregular meiosis. They are also capable of utilising pollen from 2x, 3x, or 4x donors for pseudogamous formation of endosperm.

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Monoterpenes and flavones from the leaves of Crataegus pinnatifida with anticoagulant activities

Cited by 36 publications

References 29 publications

Phytochemical composition and bioactivities of hawthorn ( Crataegus spp.): review of recent research advances

Phytochemical composition and bioactivities of hawthorn ( Crataegus spp.): review of recent research advances

New Constituents from the Low Polar Fraction of the Fruits of Crataegus dahurica and Their Anti‐Inflammatory Activity in RAW264.7 Cells

Breeding Systems in Diploid and Polyploid Hawthorns (Crataegus): Evidence from Experimental Pollinations of C. monogyna, C. subsphaerica, and Natural Hybrids

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