Monte Carlo Calculations of Energy Deposition on Cellular, Multicellular and Organ Level for Auger Emitters

Calculation of cellular S-values using Geant4-DNA: The effect of cell geometry

“…Table 3 presents cellular S-values for the radionuclides I-125, In-111 and Tc-99m. The Geant4-DNA results are compared against the MIRD database (Goddu et al, 1997) and other Monte Carlo results obtained using the in-house code MC4 (Bousis et al, 2010) and ETRAC (Ftáčniková and Böhm, 2000). As can be seen in Fig.…”

“…Since the opposite sides are the same, we will Table 3 Radionuclide cellular S-values for spherical geometry (cell radius 5 μm; nucleus radius 4 μm). MIRD data are taken from (Goddu et al, 1997) data calculated using in-house Monte Carlo code MC4 from (Bousis et al, 2010) data calculated by code ETRAC are taken from (Ftáčniková and Böhm, 2000). The statistical uncertainty of all values corresponding to 1s is below 1%.…”

“…1 8 E À 4 2.53E À 4 MC4 (Bousis et al, 2010) 3.71E À 3 2.01E À 3 6.87E À 3 6.94E À 4 4 . 1 8 E À 4 ETRAC (Ftáčniková and Böhm, 2000) 3.34E À 3 1.80E À 3 6.25E À 3 6.37E À 4 3 . (Ftáčniková and Böhm, 2000) 8.01E À 4 4 .…”

“…1 8 E À 4 ETRAC (Ftáčniková and Böhm, 2000) 3.34E À 3 1.80E À 3 6.25E À 3 6.37E À 4 3 . (Ftáčniková and Böhm, 2000) 8.01E À 4 4 . 1 3 E À 4 1.53E À 3 7.41E À 5 3.90E À 5 G4 vs. MIRD À 1.33% À 1.70% À 1.24% À 10.2% À 3.95% (Goddu et al, 1997) for the spherical geometry (cell radius 5 μm, nucleus radius 4 μm) for radionuclide sources (I-125, In-111, Tc-99m).…”

“…Ftáčniková and Böhm (2000) computed cellular S-values for several Auger emitting radionuclides using the Monte Carlo code ETRACK (Ito, 1987) and reported moderate differences (between À 18% and 21%) against the convolution integral approach. In a more detailed investigation of the validity of the CSDA, Emfietzoglou et al (2008) calculated cellular S-values for monoenergetic sources from 100 eV to 10 keV and water spheres with radius from 5 nm to 1 μm by both the convolution integral method and the Monte Carlo method using their in-house Monte Carlo code MC4 (Emfietzoglou et al, 2000).…”