Monte Carlo calculations of radiotherapy dose in “homogeneous” anatomy

Kairn, Tanya; Livingstone, A. G.; Crowe, Scott

doi:10.1016/j.ejmp.2020.09.019

Cited by 4 publications

(2 citation statements)

References 66 publications

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“…All treatments were planned in the Eclipse TPS v13.7 (Varian Medical Systems, Palo Alto, California, USA), using photon optimiser (PO) v13.7.14 and Acuros XB (AXB) v13.7.14 dose calculation algorithm with 2 mm grid size. All plans were exported from the TPS to an in-house MC system and re-calculated, using the methods previously described in the literature [ 19 , 23 ]. The in-house MC system takes the same dose grid as the TPS and performs its dose calculation.…”

Section: Methodsmentioning

confidence: 99%

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

Baker

Kairn

et al. 2023

Phys Eng Sci Med

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Gamma evaluation is currently the most widely used dose comparison method for patient specific quality assurance (PSQA). However, existing methods for normalising the dose difference, using either the dose at the global maximum dose point or at each local point, can respectively lead to under- and over-sensitivity to dose differences in organ-at-risk structures. This may be of concern for plan evaluation from clinical perspectives. This study has explored and proposed a new method called structural gamma, which takes structural dose tolerances into consideration while performing gamma analysis for PSQA. As a demonstration of the structural gamma method, a total of 78 retrospective plans on four treatment sites were re-calculated on an in-house Monte Carlo system and compared with doses calculated from the treatment planning system. Structural gamma evaluations were performed using both QUANTEC dose tolerances and radiation oncologist specified dose tolerances, then compared with conventional global and local gamma evaluations. Results demonstrated that structural gamma evaluation is especially sensitive to errors in structures with restrictive dose constraints. The structural gamma map provides both geometric and dosimetric information on PSQA results, allowing straightforward clinical interpretation. The proposed structure-based gamma method accounts for dose tolerances for specific anatomical structures. This method can provide a clinically useful method to assess and communicate PSQA results, offering radiation oncologists a more intuitive way of examining agreement in surrounding critical normal structures.

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Section: Methodsmentioning

confidence: 99%

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

Baker

Kairn

et al. 2023

Phys Eng Sci Med

Self Cite

View full text Add to dashboard Cite

show abstract

“…All treatments were planned in the Eclipse TPS v13.7 (Varian Medical Systems, Palo Alto, California, USA), using photon optimiser (PO) v13.7.14 and Acuros XB (AXB) v13.7.14 dose calculation algorithm with 2 mm grid size. All plans were exported from the TPS to an in-house MC system and re-calculated, using the methods previously described in the literature 20,24 . For each plan, the total dose le (RTDOSE, contains the total volumetric dose received by the patient) and the structure le (RTSTRUCT, contains all contoured structures) from both TPS and MC were exported in DICOM format and structure-masked dose distributions were generated using Structmask.…”

Section: Methodsmentioning

confidence: 99%

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

Baker

Kairn

et al. 2022

Preprint

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Purpose Gamma evaluation is currently the most widely used dose comparison method for patient specific quality assurance (PSQA). However, existing methods for normalising the dose difference, using either the dose at the global maximum dose point or at each local point, can respectively lead to under- and over-sensitivity to dose differences in organ-at-risk structures. This may be of concern for plan evaluation from clinical perspectives. This study has explored and proposed a new method called structural gamma, which takes structural dose tolerances into consideration while performing gamma analysis for PSQA. Methods As a demonstration of the structural gamma method, a total of 78 retrospective plans on four treatment sites were re-calculated on an in-house Monte Carlo system and compared with doses calculated from the treatment planning system. Structural gamma evaluations were performed using both QUANTEC dose tolerances and radiation oncologist specified dose tolerances, then compared with conventional global and local gamma evaluations. Results Results demonstrated that structural gamma evaluation is especially sensitive to errors in structures with restrictive dose constraints. The structural gamma map provides both geometric and dosimetric information on PSQA results, allowing straightforward clinical interpretation. Conclusion The proposed structure-based gamma method accounts for dose tolerances for specific anatomical structures. This method can provide a clinically useful method to assess and communicate PSQA results, offering radiation oncologists a more intuitive way of examining agreement in surrounding critical normal structures.

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Determining tolerance levels for quality assurance of 3D printed bolus for modulated arc radiotherapy of the nose

et al. 2021

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Monte Carlo calculations of radiotherapy dose in “homogeneous” anatomy

Cited by 4 publications

References 66 publications

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

A structure-based gamma evaluation method for identifying clinically relevant dose differences in organs at risk

Determining tolerance levels for quality assurance of 3D printed bolus for modulated arc radiotherapy of the nose

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