2012
DOI: 10.1088/0031-9155/57/12/3759
|View full text |Cite
|
Sign up to set email alerts
|

Monte Carlo simulations to support start-up and treatment planning of scanned proton and carbon ion therapy at a synchrotron-based facility

Abstract: Reliable treatment planning of highly conformal scanned ion beam therapy demands accurate tools for the determination and characterization of the individual pencil-like beams building up the integral dose delivery and related mixed radiation field. At present, clinically practicable inverse treatment planning systems (TPSs) can only rely on fast-performing analytical algorithms. However, the rapidly emerging though more computationally intensive Monte Carlo (MC) methods can be employed to complement analytical… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

3
262
0

Year Published

2013
2013
2024
2024

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 195 publications
(265 citation statements)
references
References 52 publications
3
262
0
Order By: Relevance
“…Various testing cases have been studied and good agreement between goCMC and Geant4 was observed. The Geant4 version and physics settings used in this study was validated against published experimental data (Schwaab et al ., 2011; Parodi et al ., 2013) and another experimentally validated code FLUKA (Parodi et al ., 2012). If desired, users can always use other physics data as the code input.…”
Section: Discussionmentioning
confidence: 99%
“…Various testing cases have been studied and good agreement between goCMC and Geant4 was observed. The Geant4 version and physics settings used in this study was validated against published experimental data (Schwaab et al ., 2011; Parodi et al ., 2013) and another experimentally validated code FLUKA (Parodi et al ., 2012). If desired, users can always use other physics data as the code input.…”
Section: Discussionmentioning
confidence: 99%
“…Treatment planning is performed using the first commercial CE-labelled TPS (treatment-planning system) for ions Syngo PT Planning (Siemens AG), largely based on the research code TRiP98 that was developed and clinically used for the carbon ion pilot therapy project at the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt, Germany [2]. The analytical dose calculation engine relies on a pencil-beam algorithm combining laterally integrated depth–dose distributions in water, obtained from Monte Carlo calculations [3], with an analytical radial dose spread. The first clinically used version of the code only accounted for a single Gaussian lateral beam parametrization.…”
Section: Introductionmentioning
confidence: 99%
“…Both TPS use the same experimental input data [25]. Richter compared dose distributions calculated with HIT-TPS and with TRiP98 software package and reports that the mean differences between dose distributions calculated by HIT-TPS and TRiP equal zero (STD below 1%) [32].…”
Section: Discussionmentioning
confidence: 99%
“…The physical beam-model, input data used by TRiP98 for the TP optimization and dose distribution calculation were the same as the data used by Siemens Syngo RT, software clinically used for the TP at HIT [25]. The biological optimization and dose distribution calculation for carbon ions were based on the biological model LEM I which was introduced by Scholz et al [26,27] and is currently used for therapy at HIT.…”
Section: Methodsmentioning
confidence: 99%