Mood, food, and obesity

Singh, Minati

doi:10.3389/fpsyg.2014.00925

Cited by 307 publications

(247 citation statements)

References 383 publications

(560 reference statements)

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“…Negative emotional states trigger the consumption of palatable foods with high hedonic value, providing positive gratification and comfort (Singh, 2014). However, repeated consumption of these palatable energy-dense foods, usually high in carbohydrates, sugar, and fat, increases the likelihood of obesity, and substantiates the need to clarify how affective state can impact our health.…”

Section: Introductionmentioning

confidence: 97%

The effect of emotional state on taste perception

Noel

Dando

2015

Appetite

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Section: Introductionmentioning

confidence: 97%

The effect of emotional state on taste perception

Noel

Dando

2015

Appetite

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“…Reward and gratification associated with palatable food consumption are partially mediated by abrupt dopamine (DA) increases in the nucleus accumbens and the ventral tegmental area (Singh, 2014). Moreover, the amount of DA released after consuming a preferred meal eventually correlates with the degree of experienced pleasure (Small, Jones‐Gotman, & Dagher, 2003).…”

Section: Introductionmentioning

confidence: 99%

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

et al. 2018

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IntroductionDopamine (DA) is a neurotransmitter that regulates the rewarding and motivational processes underlying food intake and eating behaviors. This study hypothesized associations of DNA methylation signatures at genes modulating DA signaling with obesity features, metabolic profiles, and dietary intake.MethodsAn adult population within the Methyl Epigenome Network Association project was included (n = 473). DNA methylation levels in white blood cells were measured by microarray (450K). Differentially methylated genes were mapped within the dopaminergic synapse pathway using the KEGG reference database (map04728). Subsequently, network enrichment analyses were run in the pathDIP portal. Associations of methylation patterns with anthropometric markers of general (BMI) and abdominal obesity (waist circumference), the blood metabolic profile, and daily dietary intakes were screened.ResultsAfter applying a correction for multiple comparisons, 12 CpG sites were strongly associated (p < 0.0001) with BMI: cg03489495 (ITPR3), cg22851378 (PPP2R2D), cg04021127 (PPP2R2D), cg22441882 (SLC18A1), cg03045635 (DRD5), cg23341970 (ITPR2), cg13051970 (DDC), cg08943004 (SLC6A3), cg20557710 (CACNA1C), cg24085522 (GNAL), cg16846691 (ITPR2), and cg09691393 (SLC6A3). Moreover, average methylation levels of these genes differed according to the presence or absence of abdominal obesity. Pathway analyses revealed a statistically significant contribution of the aforementioned genes to dopaminergic synapse transmission (p = 4.78E−08). Furthermore, SLC18A1 and SLC6A3 gene methylation signatures correlated with total energy (p < 0.001) and carbohydrate (p < 0.001) intakes.ConclusionsThe results of this investigation reveal that methylation status on DA signaling genes may underlie epigenetic mechanisms contributing to carbohydrate and calorie consumption and fat deposition.

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“…Some studies have shown that people who are depressed tend to eat comfort food to elevate their mood, thereby leading to obesity [181]. Depression can occur in adults, children and adolescents.…”

Section: G Psychological Factorsmentioning

confidence: 99%

Assessment of Obesity, Presumed and Proven Causes and Prevention Strategies: A Review

Uzogara¹

2016

AOWMC

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The obesity epidemic has been widespread in many countries, and has several adverse consequences. So many factors, some probable, others verified and documented, are known to contribute to the obesity problem in developed and developing countries. Nutritionists and other health professionals need to be skilled in understanding these various causes and their health implications. They should also be able to assess excessive body weight in clinical and other settings. Armed with this knowledge, health professionals should therefore be able to advise consumers and clients struggling with weight management on cost-effective preventive strategies to prevent or reduce incidence of obesity. In addition, nutritionists should be able to advise food manufacturers to make and market healthy food products. This paper will address the growing concern on obesity epidemic by reviewing the presumed and published or proven causes of obesity and the various methods for measurement of obesity. Strategies for preventing obesity will also be discussed. Such strategies would include health education, lifestyle changes, physical activity, diet and behaviour modifications as well as reading food labels and proper food selection. Preventive strategies for obesity and overweight when properly implemented are very cost effective especially at personal and community levels and will ensure good health and wellness in many populations. Keywords IntroductionObesity and overweight trends have reached epidemic proportions in many countries [1][2][3][4][5][6][7][8], and have serious health and socio-economic consequences. In addition, obesity has negative medical, psychological and quality of life consequences, drains health care resources and reduces life expectancy. The International Obesity Task Force (IOTF) and WHO project that obesity rates worldwide would increase very significantly by 2025 unless appropriate intervention is taken [8,9]. In the USA, between 2011 & 2012, the percent of US adults aged 20 years and above who are obese was reported to be 35.1 %, while the percent of US adults who had excess body weight (overweight and obesity)in the same period was 69.0% according to published reports [2,10]. Obesity and related chronic diseases are no longer a problem of affluent countries alone, as poor developing countries, middle income countries or countries undergoing economic transition, are also affected by the epidemic [4,[6][7][8]. Global, national and state public health agencies as well as their nutritionists, researchers and educators have raised awareness or taken immediate action to arrest the increasing weight trends and obesity in adults, the youth and children [11][12][13][14][15][16]. Despite the high prevalence of obesity in many parts of the world, segments of populations (such as geriatric, very sick people, preschool children, pregnant & lactating women) suffer from underweight [7,[17][18][19]. In some developing countries, various types of unhealthy weight such as obesity, overweight and underweight, can coexist...

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Mood, food, and obesity

Cited by 307 publications

References 383 publications

The effect of emotional state on taste perception

The effect of emotional state on taste perception

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

Assessment of Obesity, Presumed and Proven Causes and Prevention Strategies: A Review

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