Information technology plays a very important role in improving teaching effect and promoting education informatization. Cultivating talents with computer literacy through information technology education is gradually becoming a hot spot of educational development. Exploring a curriculum design platform with high efficiency, low technical threshold and simple operation has undoubtedly become the most urgent need for the development of education informatization. Therefore, this paper uses the Moodle platform to design the basic course of information technology, and meets the students’ learning needs by integrating teaching resources and giving full play to the platform’s teaching advantages. Through the platform teaching feedback experiment and teaching effect experiment, this paper analyzes whether the use of Moodle platform for information technology course teaching can improve learning interest and learning ability. The self-learning ability was improved, 76.39% of the students improved their collaborative learning ability, and 68.06% of the students improved their information processing ability.