Morbidité dans un service de pédiatrie du CHU de Brazzaville : 12 ans après (1989–2001)

Mabiala-Babela, J. R.; Samba-Louaka, C.; Mouko, A.; Senga, P.

doi:10.1016/s0929-693x(03)00290-2

Cited by 12 publications

(3 citation statements)

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“…The majority of countries (Benin, Burundi [43,44], Ethiopia [47-50], Equitorial Guinea [39-41], Gambia [51,52], Kenya [53-56], Rwanda [64], Senegal [67], United Republic of Tanzania [29-34], and Zambia [35-38]) had demonstrable progress from 2005 through 2009. Four countries (Cameroon [68]; Congo [69]; Madagascar [70]; and Sudan [71]) had early reports of little or no progress and three countries (Burkina Faso [72], Nigeria [73] and Zimbabwe [74]) had early reports of worsening malaria; more recent information on improved funding and scale-up for malaria control has been reported from these countries but is not yet adequately documented.…”

Section: Resultsmentioning

confidence: 99%

Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects

Steketee¹,

Campbell²

2010

Malar J

132

128

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BackgroundSince 2005, malaria control scale-up has progressed in many African countries. Controlled studies of insecticide-treated mosquito nets (ITNs), indoor residual spraying (IRS), intermittent preventive treatment during pregnancy (IPTp) and malaria case management suggested that when incorporated into national programmes a dramatic health impact, likely more than a 20% decrease in all-cause childhood mortality, was possible. To assess the extent to which national malaria programmes are achieving impact the authors reviewed African country programme data available through 2009.MethodsNational survey data, published literature, and organization or country reports produced during 2000-2009 were reviewed to assess available malaria financing, intervention delivery, household or target population coverage, and reported health benefits including infection, illness, severe anaemia, and death.ResultsBy the end of 2009, reports were available for ITN household ownership (n = 34) and IPTp use (n = 27) in malaria-endemic countries in Africa, with at least two estimates (pre-2005 and post-2005 intervals). Information linking IRS and case management coverage to impact were more limited. There was generally at least a three-fold increase in household ITN ownership across these countries between pre-2005 (median of 2.4% of households with at least one ITN) and post-2005 (median of 32.5% of households with at least one ITN). Ten countries had temporal data to assess programme impact, and all reported progress on at least one impact indicator (typically on mortality); in under-five year mortality rates most observed a decline of more than 20%. The causal relationship between malaria programme scale-up and reduced child illness and mortality rates is supported by biologic plausibility including mortality declines consistent with experience from intervention efficacy trials, consistency of findings across multiple countries and different epidemiologic settings, and temporal congruity where morbidity and mortality declines have been documented in the 18 to 36 months following intervention scale-up.ConclusionsSeveral factors potentially have contributed to recent health improvement in African countries, but there is substantial evidence that achieving high malaria control intervention coverage, especially with ITNs and targeted IRS, has been the leading contributor to reduced child mortality. The documented impact provides the evidence required to support a global commitment to the expansion and long-term investment in malaria control to sustain and increase the health impact that malaria control is producing in Africa.

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Section: Resultsmentioning

confidence: 99%

Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects

Steketee¹,

Campbell²

2010

Malar J

132

128

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“…In contrast, data on Central Africa are particularly scarce and show little change in the malaria situation relative to historical figures [ 23 ]. In Congo, the proportion of pediatric hospitalizations due to malaria (estimated at 30%) has remained stable [ 24 ]. Two cross-sectional studies performed in Cameroon in 2000 and 2004 indicate a slight reduction in the pediatric prevalence of asymptomatic carriage, but found no change in malaria prevalence in patients with fever [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

No evidence of decline in malaria burden from 2006 to 2013 in a rural Province of Gabon: implications for public health policy

et al. 2015

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BackgroundThe morbidity of malaria has steady declined in the urban regions of Gabon between 2000 and 2008, but caution should be exercised before generalizing this trend to the whole country because this finding has not been systematically confirmed in remote rural provinces.MethodsWe conducted a retrospective survey using data on malaria cases recorded in North Eastern Gabon between 2006 and 2013 at health facilities in Makokou. Malaria data were analyzed, and associations with annual variations and patient age were assessed.ResultsA global increase in clinical and confirmed malaria cases was observed over the study period. The rate of infection was significantly higher in children aged between 0 to 4 years than in children of 5 years and above, and in adults. Contrary to prior observations in urban and semi-urban areas of Gabon, malaria burden remained mostly unchanged or even increased in Makokou in the Ogooué-Ivindo province during these last 8 years.ConclusionsThe persistence of Plasmodium falciparum pockets of sustained malaria transmission in rural Gabon may be related to an inadequate coverage of key interventions, to poor treatment seeking behavior and/or to a decline efficacy of treatments. Our results highlight the need to better adapt malaria control strategies to local epidemiological contexts and to environmental constraints. Equitable delivery of health service to hard-to-reach populations constitutes a challenging issue for the health authorities of Gabon.Electronic supplementary materialThe online version of this article (doi:10.1186/s12889-015-1456-4) contains supplementary material, which is available to authorized users.

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“…Marasmus and kwashiorkor, which are the extreme forms of protein-energy malnutrition (PEM), account for 7 (7.3%) and 6 (6.3%) cases respectively. Mabiala-Babela et al, according to a study conducted on the evolution of morbidity in 12 years in the said department, reported malaria in first position in 32% of cases, followed by acute respiratory infections (14.4%) and then gastroenteritis in 12.4% of cases 18 .…”

Section: Discussionmentioning

confidence: 97%

Biological Profile of the Undernourished Child Hospitalized at the CHU of Brazzaville

Mikolélé-Bilombo

Ollandzobo²,

Mandilou³

2021

Int J Health Sci Res

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Background: In developing countries, the inclusion assessment of the undernourished child in hospital is limited to simple routine examinations as in any pathology. The objective of the present study is to evaluate the relevance of the biological parameters routinely requested in addition to the parameters of undernutrition per se. Material and methods: Descriptive and analytical study carried out in Brazzaville among hospitalized and malnourished children from one to 59 months. Eight biological parameters were measured: C-reactive protein, orosomucoid, albumin and transthyretin using Cobas c311; blood count using Sysmex XN350 counter, serum protein electrophoresis on HELENA chain, sedimentation rate, and HIV retroviral serology. The R software was used for statistical analysis and the significance threshold was set at 0.05. Results: The blood count of the malnourished child reported a hypochromic microcytic anemia associated with hemodilution. The SV was moderately accelerated in a non-significant manner. Inflammatory proteins were statistically higher in severe undernutrition (p˂0.001). Serum albumin disturbances were significantly lowered in acute undernutrition (AD, p˂0.001), and not significantly in chronic undernutrition (CD). Transthyretin was significantly lowered in both forms of undernutrition (p˂0.05). Regarding serum protein electrophoresis, only albumin was significantly lowered (p˂0.001), the other fractions being normal. There was no association between undernutrition and HIV. Conclusion: The dosage of nutritional and inflammatory proteins should be promoted in our health centers for the management of undernutrition. Key words: C-Reactive Protein, Orosomucoid, Albumin, Transthyretin, undernutrition.

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Morbidité dans un service de pédiatrie du CHU de Brazzaville : 12 ans après (1989–2001)

Cited by 12 publications

References 0 publications

Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects

Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects

No evidence of decline in malaria burden from 2006 to 2013 in a rural Province of Gabon: implications for public health policy

Biological Profile of the Undernourished Child Hospitalized at the CHU of Brazzaville

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