Morbidity and long-term results of subcutaneous pyelovesical bypass in chronic ureteral obstruction

This contribution tries to indicate to the clinician what kind of information can be investigated through X-ray fluorescence, what kind of information can be extracted from this spectroscopy and finally how it competes with other tools described in previous publications such as Fourier Transform Infrared or Raman spectroscopy, X-ray Absorption Near Edge Structure spectroscopy and X-ray diffraction. To attain this goal, several examples based on X-ray fluorescence experiments performed on biological samples namely concretions, medical devices, biological fluids as well as tissues are presented.Résumé. Cette contribution vise à sensibiliser le clinicien sur l'utilisation de la spectroscopie de fluorescence X en précisant le type d'échantillon pouvant être étudié et les informations exploitables. De plus, la complémentarité avec d'autres techniques analytiques présentées dans des publications précédentes, telles que les spectroscopies vibrationnelles (spectroscopie infrarouge à transformée de Fourier et Raman), la spectroscopie d'absorption des rayons X et la diffraction des rayons X est discutée. Différents résultats de mesures par spectroscopie de fluorescence X effectués sur des échantillons biologiques de différentes natures (concrétions, dispositifs médicaux, fluides et tissus biologiques) sont présentés.

Section: Heavy Elements In Medical Devicesmentioning

confidence: 99%

The crucial contribution of X-ray fluorescence spectroscopy in medicine

Bazin¹,

Foy²,

Réguer³

et al. 2022

“…Finally, we must underline that SEM plays an important role in the characterization of the surface of medical devices [39,[144][145][146][147]. Recently, we have characterized the surface state and the elastic properties of a set of JJ stents [39] on which pathological calcifications were present (Figure 15).…”

Section: Imaging Of Medical Devicesmentioning

confidence: 99%

“…It was quite a surprise for the clinicians that black marks on the surface of JJ stents to help urologists during the operation, significantly alter the surface and may ultimately serve as nucleation centers. Note that ureteral replacement devices have also been studied [147].…”

Section: Imaging Of Medical Devicesmentioning

confidence: 99%

Scanning electron microscopy—a powerful imaging technique for the clinician

Bazin¹,

Bouderlique²,

Daudon³

et al. 2022

Since its first use several decades ago, scanning electron microscopy has been used in numerous investigations dedicated to biological systems. This contribution focuses on observations on pathological calcifications in order to review several major applications of primary importance to the clinician. Among these, we highlight such observations as medical diagnostic tools in pathologies arising from primary hyperoxaluria and urinary infections.

“…We have already investigated biological samples from different organs and parts of the human body, namely kidney [177][178][179][180][181][182][183], prostate [184,185], breast [13,103], thyroid [104][105][106], cartilage [186][187][188][189][190][191][192][193], bone [194][195][196][197], tooth [198], pancreas [199], skin and hairs [53][54][55]147,165,168,[200][201][202][203] and cardiovascular system [140,204,205]. We have also investigated cells [206], mice [207][208][209][210], and medical devices [211,212], as well as chemical compounds identified in k...…”

Section: Characterization By Physicochemical Techniquesmentioning

confidence: 99%

Foreword to microcrystalline pathologies: combining clinical activity and fundamental research at the nanoscale

Bazin¹,

Daudon²,

Frochot³

et al. 2022

This contribution underlines the key role of physicochemical characterisation techniques in the area of medical research. The starting point centres on the Mid-InfraRed platform located at the Tenon hospital and dedicated to multidisciplinary functional investigations. In the last two decades, we have enhanced this platform by creating a network combining researchers from varied disciplines such as physicists, chemists, and clinicians. The resultant research dynamism is underscored by metrics such as 71 references in Pubmed and 129 in Web of Science, and the high impact of the journals in which we have published (New England Journal of Medicine, Kidney International, Chemical Review. . . ). It is of paramount importance to disseminate these physicochemical techniques among young doctors, and to establish collaborations with appropriate private companies.