Morbidity Rates and Weight Loss After Roux-en-Y Gastric Bypass, Sleeve Gastrectomy, and Adjustable Gastric Banding in Patients Older Than 60 Years old: Which Procedure to Choose?

Moon, Rena; Kreimer, Flávio; Teixeira, André; Campos, Josemberg Marins; Ferraz, Álvaro Antônio Bandeira

doi:10.1007/s11695-015-1824-2

Cited by 44 publications

(18 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies comparing types of surgery reported that RYGB was associated with greater or equal weight loss compared with sleeve gastrectomy, and both RYGB and sleeve gastrectomy were associated with more weight loss than LAGB . Most studies reported rates of resolution of type 2 diabetes, which ranged widely from 22% to 100%, apart from the study by Moon and colleagues which reported remission of diabetes a mean of 24 months post‐operatively in only 10% of patients after LAGB, 19% after RYGB, and 34% after SG . Studies generally did not find a significant difference in diabetes resolution rates in the older compared with younger group, although a higher rate of diabetes remission was reported in participants under the age of 40, compared with the ≥60 year old group in one study .…”

Section: Resultsmentioning

confidence: 99%

“…No studies found significantly greater weight loss in the older compared with younger group. Studies in which percentage total weight loss (%TWL) was reported in older people found loss of 17% to 38% after 1 to 6 years following gastric bypass and sleeve gastrectomy, and loss of 14% to 20% after adjustable gastric banding . For studies in which weight outcome was reported as percentage excess weight loss (%EWL), older persons undergoing RYGB or LSG lost 46% to 77% excess weight at 12 to 21 months, and 43% to 72% 2 to 6 years post‐operatively .…”

Section: Resultsmentioning

confidence: 99%

“…After LAGB, studies reported %EWL of 14% to 36% at 1 year, and 35% to 48% at 5 years' follow‐up . Studies comparing types of surgery reported that RYGB was associated with greater or equal weight loss compared with sleeve gastrectomy, and both RYGB and sleeve gastrectomy were associated with more weight loss than LAGB . Most studies reported rates of resolution of type 2 diabetes, which ranged widely from 22% to 100%, apart from the study by Moon and colleagues which reported remission of diabetes a mean of 24 months post‐operatively in only 10% of patients after LAGB, 19% after RYGB, and 34% after SG .…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Treatment of obesity in older persons—A systematic review

Haywood

Sumithran

2019

Obesity Reviews

View full text Add to dashboard Cite

The study aims to systematically review the available evidence regarding weight loss interventions (lifestyle, surgical, and pharmacological) for obesity in adults aged over 60 years. A search of prospective, randomized studies took place in January 2018, on Medline (Web of Science) and PubMed databases. Search terms included the following: elderly, obese, hypocaloric, pharmacotherapy, and bariatric surgery. Abstracts were screened for eligibility. A total of 256 publications regarding lifestyle interventions were identified; of these, 69 studies were eligible. As no eligible studies were identified for pharmacotherapy or bariatric surgery, the search was broadened to include non-randomized studies. Four pharmacotherapy and 66 surgery studies were included. Lifestyle intervention had similar weight loss efficacy in older compared with younger people, with positive effects on a number of relevant outcomes, including physical function and cardiovascular parameters. There was little data regarding obesity pharmacotherapy in older persons. The available data for bariatric surgery indicate comparable weight loss and resolution of type 2 diabetes, with similar or slightly higher complication rates in older compared with younger people. Older age alone should not be considered a contraindication to intensive lifestyle or surgical intervention for obesity. There are insufficient data to guide clinical decisions regarding obesity pharmacotherapy in older people. Abstract] OR RCT [Title/Abstract] OR randomly [Title/Abstract] OR random [Title/Abstract]) #1 Search ((obesity [Title/Abstract] OR obese [Title/Abstract] OR "weight loss"[Title/Abstract] OR "weight reduction"[Title/ Abstract])) AND (elderly [Title/Abstract] OR older [Title/ Abstract] OR geriatric [Title/Abstract]) HAYWOOD AND SUMITHRAN 589

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of obesity in older persons—A systematic review

Haywood

Sumithran

2019

Obesity Reviews

View full text Add to dashboard Cite

show abstract

“…However, despite its effectiveness, it is estimated that less than 1-2% of obese patients potentially eligible for bariatric surgery eventually undergo these procedures (2). This is primarily due to the high cost associated with this surgery, its associated morbidity (15-20% of major complications) and potential mortality (very limited in the last few years), and persistent social "fear" (3,4).…”

Section: Introductionmentioning

confidence: 99%

Multicenter study on the safety of bariatric endoscopy

Coll¹,

Durán²,

Breviere³

et al. 2017

Rev Esp Enferm Dig

View full text Add to dashboard Cite

“…However, there is controversy on the implementation of bariatric surgery across the age range . In fact, few data exist examining the risks and/or benefits of bariatric surgery in older adults . Interestingly, some but not all studies report that older people have smaller weight loss and comorbidity resolution following surgery.…”

Section: Introductionmentioning

confidence: 99%

Age increases MCP-1 level in association with bariatric surgery operating time and metabolic risk severity

Malin

Kaplan

et al. 2017

Obesity Science & Practice

View full text Add to dashboard Cite

SummaryObjectiveAssess the role of inflammation on operating time in younger vs. older bariatric surgery patients.MethodsFifty‐five younger (F: 46, Age: 34.9 ± 4.0 years, body mass index [BMI]: 48.2 ± 1.0 kg m−2) and 48 older (F: 34, Age: 57.0 ± 5.1 years, BMI: 46.8 ± 1.0 kg m−2) adults were studied prior to surgery. Blood pressure, glycaemic control (fasting glucose/insulin, HbA1c), lipids (high‐density lipoprotein and triglycerides) and inflammation (monocyte chemoattractant protein‐1 [MCP‐1]) were assessed. Metabolic risk severity z‐scores were calculated from clinical outcomes. Omental adipose biopsies were collected at surgery for MCP‐1 protein analysis. Operating time was used to characterize surgical difficulty.ResultsOlder vs. younger adults had higher HbA1c (P = 0.03). There was no difference in BMI, lipids, metabolic risk severity or insulin between groups, but operating time was longer in older vs. younger individuals (P = 0.04). Circulating MCP‐1 was also elevated in older vs. younger adults (P = 0.04) independent of HbA1c, although this was not explained by omental fat. Nevertheless, serum MCP‐1 was associated with increased metabolic risk severity (R = 0.27, P = 0.01). In addition, operating time was linked to HbA1c (R = 0.30, P = 0.01) and omental MCP‐1 protein (R = 0.31, P < 0.01).ConclusionsMCP‐1 is associated with longer operating time and increased metabolic risk severity in older bariatric patients independent of glycaemic control. Pre‐operative treatment of inflammation may be required to enhance surgery effectiveness.

show abstract

Morbidity Rates and Weight Loss After Roux-en-Y Gastric Bypass, Sleeve Gastrectomy, and Adjustable Gastric Banding in Patients Older Than 60 Years old: Which Procedure to Choose?

Abstract: LSG showed the lowest readmission and reoperation rate, and RYGB patients had the highest mortality rate. Weight loss and comorbidity resolution were effectively achieved in RYGB and LSG patients.

Cited by 44 publications

References 24 publications

Treatment of obesity in older persons—A systematic review

Treatment of obesity in older persons—A systematic review

Multicenter study on the safety of bariatric endoscopy

Age increases MCP-1 level in association with bariatric surgery operating time and metabolic risk severity

Contact Info

Product

Resources

About