Moringa oleifera Supplementation Improves Antioxidant Status and Biochemical Indices by Attenuating Early Pregnancy Stress in Beetal Goats

Abstract

This study investigated the effects of supplementing different levels of Moringa oleifera leaf powder (MOLP) on antioxidant status and blood biochemical indices during early gestation in Beetal goats. A total of 30 goats were randomly divided into three groups (n = 10) comprising control (basal diet without MOLP), the 1.6% MOLP supplemented group (basal diet + 1.6% MOLP), and the 3.2% MOLP supplemented group (basal diet + 3.2% MOLP). The experiment started 5 days before estrus synchronization and lasted till day 60 of gestation. The MOLP significantly increased plasma flavonoids in 1.6% as well as 3.2% supplemented group on days 40 and 60 of pregnancy, while total phenolic contents were observed to be higher in the 3.2% MOLP supplemented group throughout the experiment in comparison with the control group. The supplementation improved plasma total antioxidant capacity (TAC) by decreasing malondialdehyde (MDA) and total oxidant status (TOS) in contrast to the control group. The activities of superoxide dismutase (SOD) and peroxidase (POD) were enhanced in both supplemented groups, whereas catalase (CAT) activity was noticed to be significantly high in the 3.2% MOLP supplemented group. The protein contents were significantly elevated with 1.6 and 3.2% supplementation levels from day 40 to day 60 of the experiment. Plasma sugar level, carotenoids, progesterone profile, and hydrolytic (protease and amylase) enzymes activities were improved only when supplemented with 3.2% MOLP. The findings suggest that supplementing with 3.2% MOLP provides beneficial effects on early pregnancy stress in Beetal goats.

Dietary Moringa oleifera Alters Periparturient Plasma and Milk Biochemical Indicators and Promotes Productive Performance in Goats

“… a Vitamin and mineral premix per kg containing: Vit E 300 IU, Vit A 50,000 IU, Vit D3 80,000 IU, Ca 18.5%, Mg 8.2%, P 3.5%, Na 3%, Zn 3,200 mg, Mn 3,333 mg, Cu 800 mg, Se 24 mg, Iodate 68 mg, Co 16 mg ( 22 ) . …”

“…The MOLP and basal diet were subjected to proximate chemical compositional analysis by using standardized methods of analytical chemists ( 24 ) as also used in our previous study ( 22 ). The MOLP was also analyzed for its different biochemical elements spectrophotometrically (UV-VIS U2800, Hitachi, Japan).…”

Modulation Impacts of Moringa oleifera on Thermo Tolerance Parameters and Blood Indices in Subtropical Ewes under Heat Stress

“…Feed additives and supplementation for their antioxidant contents are used for alleviation of heat stress in small ruminants (Kassab and Mohammed 2014a, b;Kassab et al, 2017). Recent interest has grown in the use of M. oleifera for the modulation of body functions because of its macro-and micro-nutrient contents (Fahey, 2005;Razis et al, 2014;Vongsak et al, 2014;Lin et al, 2018;Afzal et al, 2020Afzal et al, , 2021Abdel-Raheem and Hassan, 2021;Giuberti et al, 2021;Al-Mufarji and Mohammed, 2022a, b). M. oleifera is an important plant rich in nutrients that are important in medicine and nutrition for both humans and animals (Oyeyinka and Oyeyinka, 2018;Gupta et al, 2018).…”

“…M. oleifera leaves are reported to contain substantial amounts of nutrients such as protein, fiber, carotenoids, and tocopherols ( Jongrungruangchok et al, 2010;Moyo et al, 2011Moyo et al, , 2012Saini et al, 2014a, b); vitamins as A, C, and E (Hekmat et al, 2015); and minerals as potassium, calcium, sodium, magnesium, iron, copper, zinc, selenium, and manganese (Hekmat et al, 2015;Al-Mufarji and Mohammed, 2022a, b). The M. oleifera contains betacarotene and other phytochemicals known for their antioxidant abilities (quercetin, kaempferol, rutin, and caffeoylquinic acids), antioxidant vitamins (A, C, and E), and antioxidant minerals (zinc and selenium) which can play important roles as anti-stress ( Jaiswal et al, 2009;Vongsak et al, 2014;Afzal et al, 2021). The current study aims to evaluate the modulatory influences of M. oleifera at rates of 50 and 100 g on thermo-tolerance parameters, blood, and metabolic status of ewes before subjecting to heat stress in arid subtropical areas.…”

The Future of Moringa Foods: A Food Chemistry Perspective

“…A supportive effect in type 2 diabetes treatment represents one of the many health benefits for which Moringa oleifera products are promoted and will be discussed in this chapter. Other health-promoting properties, such as anti-inflammatory or antioxidant effects and immune regulatory bioactivities, have been thoroughly covered elsewhere [e.g., by Lin et al ( 7 ), Xiao et al ( 8 ), and Afzal et al ( 9 )] and would go beyond the scope of this perspective.…”