Morning Glory Anomaly With Bilateral Choroidal Colobomas in a Patient With Goldenhar's Syndrome

Abstract

Abstract. A child with Goldenhar's syndrome, bilateral choroidal colobomas, and a morning glory anomaly of the optic disk in one eye is described. Bilateral posterior segment anomalies associated with Goldenhar's syndrome are rare. An association between the morning glory anomaly and Goldenhar's syndrome has not been previously reported. J Pediatr Ophthalmol Strabismus 2007;44:187-189.

A clinical and optical coherence tomography study of choroidal colobomas

“…Consensus may not always be possible in labelling them as optic disc pit or atypical coloboma, as is evident from a report by Perkins et al [16]. Chaudhuri et al [17] published a case report of possible association of morning glory syndrome with choroidal coloboma in one eye and typical choroidal coloboma and optic disc in the other eye of a patient with Goldenhar's syndrome. A careful scrutiny of the published fundus photographs, however, shows that the disc considered to be morning glory syndrome is actually a typical optic disc coloboma that can be seen in an eye with fundus coloboma (type 3, described above).…”

The clinical characteristics and imaging findings of morning glory syndrome

“…Handmann et al [8] described this rare abnormality of optic papilla in 1929, and Kindler et al [9] named it "morning glory syndrome" in 1970 because its fundus looks like morning glory in full bloom. MGS tend to have accompanied persistent hyperplastic primary vitreous, subretinal neovascular membrane formation , retinal detachment, congenital cataract, nanophthalmos, retinochoroidal coloboma, coloboma lentis, scleral coloboma, abnormality of central nervous system, central facies cranii like cenencephalocele, and other systemic diseases such as chronic renal disease [10][11][12][13][14][15][16][17][18] .…”