Morphologic and Demographic Predictors of Third Molar Agenesis

K, Carter; Worthington, Steven

doi:10.1177/0022034515581644

Cited by 111 publications

(124 citation statements)

References 53 publications

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“…The other patient was only ‘missing’ one maxillary second premolar and the four mandibular incisors. It was further noteworthy that none of the patients examined had agenesis of third molars compared with a frequency of more than 20% in the general population . About one‐third of the patients had supernumerary permanent molars presenting as fourth and even fifth molars.…”

Section: Cleidocranial Dysplasiamentioning

confidence: 89%

“…Deviations in the formation of permanent teeth are not uncommon in the general population [e.g. 6–10% of European Caucasians have agenesis of one or more teeth mesial to the third molar, the most affected teeth being, in decreasing order, the mandibular second premolar (40%), the maxillary lateral incisor (20%), the maxillary second premolar (20%), and the mandibular central incisor (4%)] , and more than 20% of European Caucasians have agenesis of at least one third molar . One cause of agenesis of this type, affecting the last tooth in each tooth group, might be late initiation of the first teeth in the group of teeth or premature degradation of the dental lamina .…”

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confidence: 99%

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Tooth formation and eruption – lessons learnt from cleidocranial dysplasia

Kreiborg

Jensen

2018

European J Oral Sciences

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The principles of formation, renewal, and eruption of teeth are discussed. Numerous genetic aberrations may affect the formation and eruption of teeth. Cleidocranial dysplasia (CCD), caused by mutations in the runt-related transcription factor 2 (RUNX2) gene, is such a condition. The dental phenotype includes problems in both tooth formation (multiple supernumerary permanent teeth) and tooth eruption (lack of shedding of primary teeth and delayed or arrested eruption of permanent teeth). Clinical studies, animal models, and molecular biology studies have documented that RUNX2 is of paramount importance for osteoblast differentiation, for regression of the dental lamina, and for osteoclastogenesis in the dental follicle and the periodontal ligament. Jensen & Kreiborg, 25 yr ago, proposed a treatment strategy to be applied to patients with CCD, focussing on the importance of early treatment to promote spontaneous eruption of permanent teeth through extraction of primary teeth, surgical removal of supernumerary teeth, and removal of bone covering the first formed permanent teeth at the time when root formation of the permanent teeth has reached half or two-thirds of their final length. This strategy still seems valid and seems to lead to reduction in the burden of care for patients compared with the treatment protocols otherwise recommended.

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Section: Cleidocranial Dysplasiamentioning

confidence: 89%

mentioning

confidence: 99%

Tooth formation and eruption – lessons learnt from cleidocranial dysplasia

Kreiborg

Jensen

2018

European J Oral Sciences

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“…According to Carter and Worthington [26], 2769 patients was the highest sample used so far. We investigated till date the largest sample size to determine prevalence of third molar agenesis in comparison with previous studies.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Third Molar Agenesis: Associated Dental Anomalies in Non-Syndromic 5923 Patients

Sujon¹,

Alam²,

Rahman³

2016

PLoS ONE

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The aim of this study was to investigate the prevalence of third molar agenesis and other associated dental anomalies in Bangladeshi population and to investigate the relationship of other dental anomalies with the third molar presence/agenesis. A retrospective study was performed using panoramic radiographs of 5923 patients, who ranged in age from 10 to 50 years. All radiographs were analyzed by Planmeca Romexis® 3.0 software (Planmeca Oy, Helsinki, Finland). Pearson chi-square and one way ANOVA (Post Hoc) test were conducted. The prevalence of third molar agenesis was 38.4%. The frequency of third molar agenesis was significantly higher in females than males (p <0.025). Third molar agenesis was significantly more prevalent in maxilla as compared to mandible (p <0.007). The prevalence of other dental anomalies was 6.5%, among them hypodontia was 3.1%. Prevalence of third molar agenesis varies in different geographic region. Among the other dental anomalies hypodontia was more prevalent.

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“…Evolutionary arisen lack of space in the dental arch often results in impaction of the last teeth to erupt, the third molars. Along with frequent aberrant follicle orientation, this leads to increasing third molar impaction prevalence with numbers varying from 17% to 32% …”

Section: Introductionmentioning

confidence: 99%

Radiographic prediction of mandibular third molar eruption and mandibular canal involvement based on angulation

Vranckx

Ockerman

Coucke

et al. 2019

Orthod Craniofacial Res

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Structured Abstract Objectives The aim of our study was to identify and predict patients at risk of impeded mandibular third molar eruption and potential relation between the third molar roots and the mandibular canal, based on molar angulations in an early development stage. Setting and Sample Population A total of 1011 adolescent orthodontic patients were included in this longitudinal study. Materials and Methods We analysed pre‐eruptive rotational changes and root development of mandibular third molars on 2022 panoramic radiographs (two time‐points). Five variables were evaluated: third molar eruption level, development stage, risk of relation between the third molar and the mandibular canal, the molar angulations and orthodontic treatment. The relation between early third molar angulation and mean annual angulation change was assessed using a linear mixed model. Logistic regression was applied to investigate a potential correlation of the radiographic variables with the eruption potential and risk of developing a relation between the third molar and the mandibular canal. Results Mandibular third molar follicles with an initial angulation exceeding 27.0° relative to the second molar tend to progressively increase their angulation during further development. A significant correlation was found between the hemimandibular molar angulations and the probability of eruption (P < 0.0001). The second to first molar angulation was predictive for potential development of a relation with the mandibular canal (P = 0.005). Conclusion From the present data, it appears that severely angulated mandibular third molars (>27.0°) have a minimal chance of future eruption and a maximal risk of developing a relation with the mandibular canal.

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Morphologic and Demographic Predictors of Third Molar Agenesis

Cited by 111 publications

References 53 publications

Tooth formation and eruption – lessons learnt from cleidocranial dysplasia

Tooth formation and eruption – lessons learnt from cleidocranial dysplasia

Prevalence of Third Molar Agenesis: Associated Dental Anomalies in Non-Syndromic 5923 Patients

Radiographic prediction of mandibular third molar eruption and mandibular canal involvement based on angulation

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