Morphologic and Histologic Changes in Hysterectomies After NovaSure Ablation: A Retrospective Chart Review

Ferguson, James; Kot, Estera; Thiel, Luke; Karreman, Erwin; Rattray, Darrien; Thiel, John

doi:10.1016/j.jmig.2015.08.685

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“…Novasure (Hologic, Inc., Marlborough, MA), radiofrequency-induced endometrial ablation (RFIEA), widely used in AUB and achieved good effects. [1–3]…”

Section: Introductionmentioning

confidence: 99%

Radiofrequency-induced endometrial ablation for the treatment of postpartum hemorrhage after vaginal delivery

Zhang

Hanbing

2017

Medicine

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“…Novasure (Hologic, Inc., Marlborough, MA), radiofrequency-induced endometrial ablation (RFIEA), widely used in AUB and achieved good effects. [1–3]…”

Section: Introductionmentioning

confidence: 99%

Radiofrequency-induced endometrial ablation for the treatment of postpartum hemorrhage after vaginal delivery

Zhang

Hanbing

2017

Medicine

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Predictors of a Successful Bipolar Radiofrequency Endometrial Ablation

Eisele

Köchli

Städele

et al. 2019

Geburtshilfe Frauenheilkd

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Introduction The studyʼs objectives were to determine the success rate following radiofrequency endometrial ablation to treat abnormal menstrual bleeding and to assess risk factors for failure of the method. Materials and Methods 195 women who were treated with bipolar radiofrequency endometrial ablation between 01/2009 and 06/2016 were included in this prospective cohort study. Postoperative data from 187 women were collected at a median of 17.5 months (IQR 4.5–34.9; 1–82). Multivariate analyses of risk factors were performed. Success was defined as amenorrhoea or spotting. Results Patient characteristics were as follows: mean age 44 years (SD ± 5), median parity 2 (IQR 2–3), median hysterometer 8.7 cm (SD ± 1.1), and median BMI 23.5 kg/m2 (IQR 21–27). 30 patients (19.5%) had intramural masses that could be measured with ultrasound. Postoperative success rate was 86.1%. 10 patients (5%) had a hysterectomy postoperatively – 6 for heavy bleeding, 3 due to prolapse, and 1 due to dysmenorrhoea. Multivariate analyses showed the presence of intramural masses in women < 45 years was a significant risk factor for therapeutic failure (p = 0.033; 95% CI 1.08–12.57), with an increased risk of hysterectomy (OR 7.9, 95% CI 1.2–52.7, p = 0.033). Conclusion Bipolar radio frequency endometrial ablation was highly successful in the absence of an intramural mass (88%). Even smaller intramural fibroids (DD: adenomyomas of a median of 15 mm) reduce the success rate (76%), which is why preoperative ultrasound is recommended. In the presence of intramural masses, the risk of a hysterectomy for women < 45 years increases eightfold.

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Morphologic and Histologic Changes in Hysterectomies After NovaSure Ablation: A Retrospective Chart Review

Cited by 2 publications

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Radiofrequency-induced endometrial ablation for the treatment of postpartum hemorrhage after vaginal delivery

Radiofrequency-induced endometrial ablation for the treatment of postpartum hemorrhage after vaginal delivery

Predictors of a Successful Bipolar Radiofrequency Endometrial Ablation

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