Morphologic changes in collagen fibers after 830 nm diode laser welding

Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence*

“…When irradiated, ®broblasts assume a polarised pattern, forming bundles in different directions. Some authors [8,57] have already reported this ®nding. If it also happens in vivo it could explain both the better aesthetic healing and the less wound contracture obtained after surgeries using laser than conventional surgeries.…”

Microscopic characterization of collagen modifications induced by low‐temperature diode‐laser welding of corneal tissue

“…Shober et al [42] observed an increase in fibril caliber, a loss of periodicity, and a splitting into fine fibrillar substructures. A similar effect was seen in dura mater subjected to CO 2 laser irradiation [6], in tendon specimens heated at 608C for 20 minutes in a water bath [43], in joint capsular collagen under Holmium:YAG laser irradiation [44], and in diode laser-assisted anastomosis of arteries performed without exogenous chromophores at a relatively high diode laser power density of 250 W/cm 2 [45]. In all these cases, high temperatures or long exposure times promoted partial collagen denaturation that was characterized by an unwinding of the triple helix and a subsequent loss of fibrillar integrity.…”

An experimental study on laser-induced suturing of venous grafts in cerebral revascularization surgery

“…This effect was found to increase with the laser fluence. In fact, the collagen of the media layer turns into a hyalin matrix, an effect that was demonstrated also in previous works [15][16][17][18] . The fact that laser injury did not promote myointimal hyperplasia or endothelial damage in laser-assisted bypass may be related to the observation of a constant integrity of the tunica elastica interna in the arterial versant of the bypass or to disorganization of sub-endothelial collagen fibers in the venous versant.…”