Morphologic features of the normal aortic arch in neonates, infants, and children pertinent to growth

Abstract

Morphologic features of the normal aortic arch in neonates, infacnts, and children pertinent to growth Machii, M.; Becker, A.E.

Hypoplastic aortic arch morphology pertinent to growth after surgical correction of aortic coarctation

“…The present study confirms that the hypoplastic segment has a significantly lower number of elastin lamellae than normal (p < 0.02) [10]. However, the ratio obtained by dividing the number of elastin lamellae by the diameter is significantly higher than normal (p < 0.02).…”

“…However, we are not aware of any study correlating morphometric data of the hypoplastic segment with its histologic features. The results of this study are interpreted in light of the results obtained in our previous study of growth characteristics of normal aortas [10].…”

“…An additional feature, albeit unrelated to length, is the fact that once we compared collagen density of the media of the hypoplastic segment with previously obtained data from normal aortas [10], the hypoplastic segment had significantly more collagen than normal. This feature is already evident at the time of birth.…”

Towards the modelling of ageing and atherosclerosis effects in ApoE-/- mice aortic tissue

“…Several studies investigate the morphological, structural, and biochemical changes of the aorta as well as the relation between these changes and the mechanics of the aorta, see [9,16,20,32,33]. These studies confirm that the aorta increases its stenosis ratio, wall thickness, and mechanical stiffness during atherosclerosis.…”

“…with E = λ 2 z sin(β) 2 + λ 2 θj cos(β) 2 − 1 by means of equations (20,21) calculate internal pressure…”