Morphological and Histochemical Studies on the Cardiac Conduction System of the Dog

Hara, T

doi:10.1679/aohc1950.28.227

Cited by 13 publications

(3 citation statements)

References 35 publications

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“…According to our results, the LBBP lead tips in all 6 canines were placed in the LSF regions by only one attempt, implying the feasibility of the triangle‐center method identified by TVA angiography for LBBP lead deployment. According to the morphological study of canine conduction system by Hara et al, 25 the rich intermediate ramification of the left bundle (the LSF) caused more Purkinje fibers in the left side of the septum than the right side. Our triangle‐center method for LFS capture was developed based on this anatomical basis.…”

Section: Discussionmentioning

confidence: 99%

“…23,24 The main advantage of our approach was that the right side of the interventricular septum could be clearly displayed by TVA angiography under RAO 30°. The pacing lead could be easily and correctly to the morphological study of canine conduction system by Hara et al, 25 the rich intermediate ramification of the left bundle (the LSF) caused more Purkinje fibers in the left side of the septum than the right side. Our triangle-center method for LFS capture was developed based on this anatomical basis.…”

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confidence: 99%

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A novel approach for developing left bundle branch pacing and left bundle branch block in a canine model

Cheng

et al. 2023

Cardiovasc electrophysiol

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Background and Objective Left bundle branch pacing (LBBP) has shown the benefits in the treatment of dyssynchronous heart failure (HF). The purpose of this study was to develop a novel approach for LBBP and left bundle branch block (LBBB) in a canine model. Methods A “triangle‐center” method by tricuspid valve annulus angiography for LBBP implantation was performed in 6 canines. A catheter was then applied for retrograde His potential recording and left bundle branch (LBB) ablation simultaneously. The conduction system was stained to verify the “triangle‐center” method for LBBP and assess the locations of the LBB ablation site in relation to the left septal fascicle (LSF). Results The mean LBB potential to ventricular interval and stimulus‐peak left ventricular activation time were 11.8 ± 1.2 and 35.7 ± 3.1 ms, respectively. The average intrinsic QRS duration was 44.7 ± 4.7 ms. LBB ablation significantly prolonged the QRS duration (106.3 ± 8.3 ms, p < .001) while LBBP significantly shortened the LBBB‐QRS duration to 62.5 ± 5.3 ms (p < .001). After 6 weeks of follow‐up, both paced QRS duration (63.0 ± 5.4 ms; p = .203) and LBBB‐QRS duration (107.3 ± 7.4 ms; p = .144) were unchanged when comparing to the acute phase, respectively. Anatomical analysis of 6 canine hearts showed that the LBBP lead‐tip was all placed in LSF area. Conclusion The new approach for LBBP and LBBB canine model was stable and feasible to simulate the clinical dyssynchrony and resynchronization. It provided a useful tool to investigate the basic mechanisms of underlying physiological pacing benefits.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

A novel approach for developing left bundle branch pacing and left bundle branch block in a canine model

Cheng

et al. 2023

Cardiovasc electrophysiol

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“…The right bundle branch does not emanate any branches until it reaches the base of the papillary muscle, and then it sends branches to the subendocardial plexus of Purkinje fibers, conus arteriosus, and free wall of the RV. [9][10][11] In many subjects (38%), the moderator band does not contain ordinary cardiac muscle but is purely a system of conductive tissue (Purkinje fibers and nerves). 7,8 This particular patient responded well to lead removal from the moderator band region and had complete relief of symptoms.…”

Section: A B Cmentioning

confidence: 99%

Chest Pain Associated with Moderator Band Pacing

Goli¹,

Kaszala²,

Lucke³

et al. 2014

Texas Heart Institute Journal

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T ransvenous pacing with an implanted pacemaker has become the treatment of choice for cardiac rhythm disturbances such as sinus node dysfunction and complete heart block.1-5 Transvenous pacing leads are inserted with fluoroscopic guidance and positioned in the right atrium and right ventricle (RV). In most patients, the right atrial appendage is the optimal location for the right atrial lead. However, the optimal position of the RV lead varies in accordance with RV anatomy (dimensions and orientation of the RV in the thorax), the presence of tricuspid regurgitation or cardiomyopathy, the patient's history of infarction, and the operator's experience. After pacemaker placement, ventricular cardiac pacing stimuli might cause acute or chronic chest pain, which usually is associated with cardiac perforation that requires emergency evaluation and treatment. 6 We treated a patient who had chronic chest pain associated with placement of the RV lead in a calcified moderator band. We discuss the treatment and results. Case ReportA 65-year-old man was evaluated because of chronic chest pain. His medical history included inducible ventricular tachycardia, which had been treated 8 years earlier with a dual-chamber implantable cardioverter-defibrillator (ICD). The right atrial lead was model 4470, and the RV lead was model 0185 of the Endotak Reliance ® G (Boston Scientific Corporation; Natick, Mass).At the time of ICD implantation, the patient had been treated with sotalol; a coronary angiogram had shown nonobstructive coronary artery disease and a left ventricular ejection fraction of 0.45 to 0.50, consistent with mild idiopathic nonischemic cardiomyopathy. The chest pain had begun after implantation of the ICD and had persisted until his current presentation, 8 years later. The patient's medical history was also notable for hypertension, severe emphysematous chronic obstructive pulmonary disease, esophageal stricture (previously treated with dilation), and stroke. His body mass index was 23 kg/m 2 . We determined that the patient needed elective replacement of the ICD generator. He reported a chronic poking sensation in the chest, which was reproduced at the minimum RV pacing threshold, but not by manipulating the ICD pulse-generator pocket. He tolerated atrial pacing well and had no chest pain during high-rate atrial pacing. There was normal lead-integrity response to both left pectoral muscle isomet-

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Anatomy of the Conduction System

Oliveira¹

2018

Guide to Canine and Feline Electrocardiography

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Morphological and Histochemical Studies on the Cardiac Conduction System of the Dog

Cited by 13 publications

References 35 publications

A novel approach for developing left bundle branch pacing and left bundle branch block in a canine model

A novel approach for developing left bundle branch pacing and left bundle branch block in a canine model

Chest Pain Associated with Moderator Band Pacing

Anatomy of the Conduction System

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