Morphological and molecular characterization supporting Amblyomma mixtum presence in Cuba

Encinosa, Pedro E.; García, Yuselys; Lleonart, Ricardo; Aliaga, Daniela; Fernández, Yilian; Bello, Yamil; Guardia, Carolina De La; González, Yorexis; Díaz, Angelina; Estrada, Mario Pablo; Rodríguez-Mallón, Alina

doi:10.1016/j.ttbdis.2020.101602

Cited by 3 publications

(3 citation statements)

References 24 publications

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“…Data of species' distribution were downloaded from the Global Biodiversity Information Facility (GBIF; https://www.gbif.org/, accessed on 13 January 2023). (S1 Dataset) In addition, we implemented a literature review to complete the occurrence data from Web of Science and PubMed database, for which the time range was 1970-2020 [11,12,[15][16][17][18][19][20][21][22][23][24][25]. These distribution points were filtered to remove duplicates and missing records.…”

Section: Species Distributionmentioning

confidence: 99%

Predicting the global potential distribution of two major vectors of Rocky Mountain Spotted Fever under conditions of global climate change

Ji,

Wei,

et al. 2024

PLoS Negl Trop Dis

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Rocky Mountain spotted fever is a tick-borne disease that is highly dangerous but often overlooked by the public. To prevent the spread of the disease, it is important to understand the distribution patterns of its vectors’ suitable areas. This study aims to explore the potential global suitability of areas for the vectors of Rocky Mountain spotted fever, including Dermacentor variabilis and Amblyomma cajennense under both historical and future climate scenarios. The study also seeks to investigate the impact of climatic factors on the distribution patterns of these vectors. Data on species distribution were downloaded from the Global Biodiversity Information Facility, Web of Science and PubMed database. The climatic variables were downloaded from WorldClim Global Climate Database. The Maximum Entropy Model was used to evaluate the contribution of monthly precipitation, monthly maximum temperature, monthly minimum temperature, elevation, and nineteen other climatic variables to vector survival, as well as to predict the suitable area for the vectors. We found that D. variabilis is distributed in North America, while A. cajennense is mainly distributed in South America, but all other continents except Antarctica have a suitable distribution. D. variabilis is more likely to survive in temperate regions, and A. cajennense is more likely to survive in tropical zones. D. variabilis is more sensitive to temperature, whereas A. cajennense is sensitive to both temperature and precipitation, and A. cajennense prefers tropical regions with hot and humid characteristics. The high suitable areas of both vectors were almost expanded in the ssp5-8.5 scenario, but not so much in the ssp1-2.6 scenario. Highly suitable areas with vectors survival should be strengthened with additional testing to prevent related diseases from occurring, and other highly suitable areas should be alert for entry and exit monitoring to prevent invasion and colonization of vectors.

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Section: Species Distributionmentioning

confidence: 99%

Predicting the global potential distribution of two major vectors of Rocky Mountain Spotted Fever under conditions of global climate change

Ji,

Wei,

et al. 2024

PLoS Negl Trop Dis

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“…En México, A. mixtum está asociada a bovinos y équidos; sin embargo, puede parasitar varios hospederos, incluyendo humanos (Rodríguez-Vivas et al 2016, Aguilar-Domínguez et al 2018, Encinosa et al 2021. A pesar de su amplia distribución, y que México ofrece las condiciones necesarias para su proliferación, el L conocimiento sobre ésta garrapata es escaso.…”

Section: Ambylomma Mixtum: La Otra Garrapata Del Bovinounclassified

Amblyomma mixtum: la otra garrapata del bovino

Romero-Salas

Bravo‐Ramos

Sánchez‐Montes

2022

BAC

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“…Besides dogs, they can be found on a diverse range of wild and domestic animals, including humans [18][19][20], and some pathogens that they transmit are zoonotic [20]. Amblyomma mixtum (Koch, 1844) is another important tick species found in Cuba [21]. They inhabit peridomestic environments and have a three-host life cycle, parasitizing humans, livestock, and wildlife.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of the Vaccine Candidate Based on the P0 Peptide against Dermacentor nitens and Ixodes ricinus Ticks

Rodríguez-Mallon,

Encinosa Guzmán,

Bello

et al. 2023

Pathogens

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The control of ticks through vaccination offers a sustainable alternative to the use of chemicals that cause contamination and the selection of resistant tick strains. However, only a limited number of anti-tick vaccines have reached commercial realization. In this sense, an antigen effective against different tick species is a desirable target for developing such vaccines. A peptide derived from the tick P0 protein (pP0) conjugated to a carrier protein has been demonstrated to be effective against the Rhipicephalus microplus, Rhipicephalus sanguineus, and Amblyomma mixtum tick species. The aim of this work was to assess the efficacy of this peptide when conjugated to the Bm86 protein against Dermacentor nitens and Ixodes ricinus ticks. An RNAi experiment using P0 dsRNA from I. ricinus showed a dramatic reduction in the feeding of injected female ticks on guinea pigs. In the follow-up vaccination experiments, rabbits were immunized with the pP0-Bm86 conjugate and challenged simultaneously with larvae, nymphs, and the adults of I. ricinus ticks. In the same way, horses were immunized with the pP0-Bm86 conjugate and challenged with D. nitens larva. The pP0-Bm86 conjugate showed efficacies of 63% and 55% against I. ricinus and D. nitens ticks, respectively. These results, combined with previous reports of efficacy for this conjugate, show the promising potential for its development as a broad-spectrum anti-tick vaccine.

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Morphological and molecular characterization supporting Amblyomma mixtum presence in Cuba

Cited by 3 publications

References 24 publications

Predicting the global potential distribution of two major vectors of Rocky Mountain Spotted Fever under conditions of global climate change

Predicting the global potential distribution of two major vectors of Rocky Mountain Spotted Fever under conditions of global climate change

Amblyomma mixtum: la otra garrapata del bovino

Efficacy of the Vaccine Candidate Based on the P0 Peptide against Dermacentor nitens and Ixodes ricinus Ticks

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