Morphological Characteristics of the Inner Medullary Zone in the Kidneys of Brattleboro and Wistar Rats during Blockade of Prostaglandin Synthesis

Abstract

Morphological characteristics of the inner medullary zone in the kidneys in Brattleboro and Wistar rats were studied during blockade of prostaglandin synthesis. The absence of a diuretic effect of prostaglandins on the kidneys was accompanied by structural changes in the transepithelial and interstitial barriers for an osmotic flow of water.