Morphological Features of the Human Placenta and its Free Chorionic Villi in Normal Pregnancies and those with Diabetes and High Blood Pressure. Literature Review

Prieto-Gómez, Ruth; Ottone, Nicolás Ernesto; Bianchi, H.

doi:10.4067/s0717-95022018000401183

“…The chorionic plate is covered by the amnion. The umbilical cord is usually located in a slightly eccentric position in the placenta, but there are other types of placement, such as marginal umbilical cord placement, wherein the umbilical cord is attached laterally, or membranous attachment of the umbilical cord, wherein the umbilical vessels are present on the surface of the amniotic membranes at some distance from the edge of the placenta, surrounded only by a fold in the amnion, so they are outside the placenta [ 29 , 30 ]. In such a case, if the amniotic membranes rupture, that rupture will lead to the interruption in the continuity of the umbilical vessels, the consequence of which may be bleeding and fetal death.…”

Section: Discussionmentioning

confidence: 99%

“…The chorionic veins are the result of the fusion of the villous veins (stalk villi, attached to the plate) and usually intersect beneath the chorionic arteries. Chorionic veins give rise to a single umbilical vein [ 29 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

Histopathological Aspects of the Influence of Babesia microti on the Placentas of Infected Female Rats

Jasik,

Kleczka,

Franielczyk

2024

Veterinary Sciences

View full text Add to dashboard Cite

Babesiosis is perceived mainly an animal disease; however, awareness that Babesia spp. parasites that can cause diseases in humans is increasing significantly. Babesiosis is spread by the bite of an infected tick (Ixodes spp.), but it can also be transmitted by transfusion of infected blood and from an infected mother to her child during pregnancy or childbirth. The parasites multiply in the bloodstream and destroy red blood cells. This study aimed to assess the influence of Babesia microti on the histological structure of the placenta. Histopathological material collected from pregnant rats infected with Babesia microti was used in the experiment. Microscopic images of the placentas were assessed by Mallory staining and by using methylene blue-stained semi-thin sections. In addition, FISH was used to detect parasite DNA. The presence of piroplasms in both maternal and fetal vessels was demonstrated. Babesia microti infection caused vacuolization of syncytioblasts and cytotrophoblasts, accumulation of collagen fibers in placental villi, and increased adhesion of erythrocytes to the vascular walls. These results indicate that Babesia may influence the course of pregnancy and invite further research on the mechanism of piroplasm penetration into cells.

show abstract

“…Hypertension is known as the leading cause of stillbirth by affecting the development of the placenta by restricting nutrient and oxygen flow to the foetus. Also, it increases the risk of abnormal bleeding between the placenta and uterine walls leading to placenta abruption [ 40 ]. All these causes foetal distress and subsequently death.…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Awareness, and Control of Hypertensive Disorders amongst Pregnant Women Seeking Healthcare in Ghana

Boachie-Ansah,

Anto,

Marfo

et al. 2023

Journal of Pregnancy

View full text Add to dashboard Cite

Hypertensive disorders in pregnancy (HDPs) are no longer seen as “transitory diseases cured by delivery.” It accounts for up to 50% of maternal deaths. Information concerning HDPs is less in developing countries like Ghana. This study was conducted to find out the prevalence, awareness, risk factors, control, and the birth outcomes of HDPs. This was a retrospective cohort study conducted among pregnant women seeking care in selected health facilities in the Ashanti Region. Data on demographics, HDPs, and its associated birth outcomes were collected. Logistic regression models were used to examine the association of the independent variables with HDPs. The burden of HDPs was 37.2% among the 500 mothers enrolled with chronic hypertension superimposed with preeclampsia accounting for 17.6%, chronic hypertension, 10.2%, and preeclampsia 6.8% whilst gestational hypertension was 2.6%. It was observed that 44% (220) of the mothers had excellent knowledge on HDPs. Oral nifedipine and methyldopa were frequently used for HDP management, and it resulted in a significant reduction in HDP burden from 37.2% to 26.6%. Factors that influenced the increased risk of HDPs were grand multigravida ( AOR = 4.53 ; CI = 1.42 –14.42), family history of hypertension ( AOR = 3.61 ; CI = 1.89 –6.90), and the consumption of herbal preparations ( AOR = 2.92 ; CI = 1.15 –7.41) and alcohol ( AOR = 4.10 ; CI = 1.34 -12.62) during pregnancy. HDPs increased the risk of preterm delivery ( AOR = 2.66 ; CI = 1.29 –5.89), stillbirth ( AOR = 12.47 ; CI = 2.72 –57.24), and undergoing caesarean section ( AOR = 1.70 ; CI = 1.10 –2.61) amongst mothers during delivery. The burden of HDPs is high amongst pregnant mothers seeking care in selected facilities. There is the need for intensified campaign on HDPs in the Ashanti Region of Ghana.

show abstract

“…The placental weight/fetal weight ratio was shown to be greater in GDM and is primarily connected with histological changes among the morphological variations. 17 One of the limitations of the study was that as the Anatomy Department has no histopathologic study facilities of its own, we have to depend on the Histopathology Department of the Medical College. So, processing of the specimen was hampered to some extent ion some cases.…”

Section: Discussionmentioning

confidence: 99%

Placental Morphological Pattern in Diabetic Pregnant Women in Comparison to Non-diabetic Pregnant Women

Khanom,

Jomrud Mohol,

Sharmin

et al. 2023

TAJ: J of Teachers Assoc

0

View full text Add to dashboard Cite

Background: The placenta of diabetic women has attracted much interest to the researchers from different disciplines, largely because it is thought that placental damage or dysfunction may be partially responsible for the unduly high incidence of perinatal complications in maternal diabetes. As postnatal placental examination is of immense significance to understand the fetal and perinatal conditions in antenatal and perinatal periods due to placental dysfunction or compromise resulting from diabetes in pregnancy. Objectives: The aim of this study was toinvestigate the morphological changes in placenta of pregestational and gestational diabetes mellitus. Methods: This cross-sectional comparative study was carried out in the Department of Anatomy, Rajshahi Medical College, Rajshahi in collaboration with the Department of Obstetrics & Gynae, Rajshahi Medical College Hospital and Diabetic Hospital Rajshahi, Bangladesh over a period of three years from January 2019 to December 2021. The study was conducted on 70 pregnant women, among them 35 women were diabetic and 35 women were non-diabetic. Then shape, weight, thickness and diameter of placenta were compared between diabetic and non-diabetic pregnant women. Data were analyzed by SPSS software, version 24 and p value < 0.05 was considered statistically significant for all tests. Results: The study revealed that majority of the diabetic mothers (54.3%) and non-diabetic mothers (60%) were within the age range of 20-30 years. The BMI of diabetic mothers was 27.7±1.8 kg/m2 and non-diabetic mothers was 26.7±1.7 kg/m2. The shape of the placenta was not affected by pregestational diabetes or GDM with oval-shaped placenta being predominant in either group (p = 0.478). Forty percent of the placenta from diabetic mothers were heavier (weighed > 500 gm) as compared to 5.7% of placenta from the non-diabetic pregnant women (p = 0.001). Over two-thirds (68.6%) of the placenta of the former group were larger (≥ 400 cc) as opposed to 14.3% of the non-diabetic mothers (p < 0.001). Thickness and diameter of the placenta were fairly comparable between the study groups (p = 0.445 and p = 0.164, respectively). Conclusion: The study concluded that placentas of diabetic mothers are significantly larger and heavier than those of the non-diabetic mothers. Thickness and diameter of the placenta were also greater in pregnant mothers with diabetes or GDM than those in non-diabetic mothers. TAJ 2023; 36: No-2: 129-134

show abstract

Morphological Features of the Human Placenta and its Free Chorionic Villi in Normal Pregnancies and those with Diabetes and High Blood Pressure. Literature Review

Abstract: Morphological features of the human placenta and its free chorionic villi in normal pregnancies and those with diabetes and high blood pressure. literature review.

Cited by 6 publications

References 34 publications

Histopathological Aspects of the Influence of Babesia microti on the Placentas of Infected Female Rats

Histopathological Aspects of the Influence of Babesia microti on the Placentas of Infected Female Rats

Prevalence, Awareness, and Control of Hypertensive Disorders amongst Pregnant Women Seeking Healthcare in Ghana

Placental Morphological Pattern in Diabetic Pregnant Women in Comparison to Non-diabetic Pregnant Women

Contact Info

Product

Resources

About