Morphological signs of inflammatory activity in different clinical forms of drug-resistant pulmonary tuberculosis

Elipashev, A. A.; Nikolsky, V. O.; Шпрыков, А. С.

doi:10.17116/patol201779413-17

“…Таким же образом действуют и сульфатиды, вырабатываемые МБТ. Вирулентные МБТ обладают способностью покидать фаголизосому и продолжать внутриклеточное размножение, что также является одним из способов защиты МБТ от фагоцитоза [6,29]. Гибель МБТ внутри макрофага происходит в результате сложных, опосредованных цитокинами, взаимодействий лимфоцитов и фагоцитов.…”

unclassified

“…То есть не само появление устойчивых форм, а их способность интенсивно размножаться в организме может являться причиной неэффективности антибактериальной терапии при появлении лекарственной устойчивости. При этом ЛУ-формы МБТ чаще встречаются у больных с различными осложнениями туберкулеза на фоне сниженного иммунитета [4,6,7,12,19].…”

unclassified

Specific Features of the Immune Response to Tuberculosis When Drug Susceptible and Drug Resistant Strains of M. Tuberculosis Are Detected

Shovkun¹,

Kudlay²,

Nikolenko³

et al. 2019

TIBL

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В обзоре представлены данные литературы о формировании иммунного ответа при туберкулезе, об особенностях клеточного и гуморального звена в зависимости от выделения лекарственно-чувствительных и лекарственно-устойчивых штаммов M. tuberculosis. Показана роль цитокинов, генетических факторов при нарушениях иммунных реакций, влияющих на патоморфоз и клинические проявления туберкулеза.

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Modification of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant in the surgical treatment of widespread destructive pulmonary tuberculosis

Тарасов

¹

,

Sadovnikova

²

,

Krasnikova

³

et al. 2023

vmirvz

0

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An observation from practice is given – surgical treatment of a patient with widespread destructive pulmonary tuberculosis due to a modified technique of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant. Patient A., 37 years old, has been suffering from pulmonary tuberculosis for 2 years. She was admitted to the clinic with complaints of shortness of breath during exercise (mrc 3), cough, back pain. On computed tomography of the chest organs: a picture of fibrous-cavernous tuberculosis of the left lung with extensive mediastinal pulmonary hernia. The patient underwent transsternal occlusion of the left main bronchus with plastic surgery of the anterior mediastinum with a polymer mesh implant. The result of the treatment was the stabilization of the process and the clinical cure of the patient.

show abstract

Modification of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant in the surgical treatment of widespread destructive pulmonary tuberculosis

Тарасов

¹

,

Sadovnikova

²

,

Krasnikova

³

et al. 2023

vmirvz

1

0

View full text Add to dashboard Cite

An observation from practice is given – surgical treatment of a patient with widespread destructive pulmonary tuberculosis due to a modified technique of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant. Patient A., 37 years old, has been suffering from pulmonary tuberculosis for 2 years. She was admitted to the clinic with complaints of shortness of breath during exercise (mrc 3), cough, back pain. On computed tomography of the chest organs: a picture of fibrous-cavernous tuberculosis of the left lung with extensive mediastinal pulmonary hernia. The patient underwent transsternal occlusion of the left main bronchus with plastic surgery of the anterior mediastinum with a polymer mesh implant. The result of the treatment was the stabilization of the process and the clinical cure of the patient.

show abstract

Morphological signs of inflammatory activity in different clinical forms of drug-resistant pulmonary tuberculosis

Abstract: The findings suggest that the activity of tuberculous inflammation is associated with different clinical forms of drug-resistant tuberculosis and with a spectrum of drug resistance.

Cited by 4 publications

References 2 publications

Specific Features of the Immune Response to Tuberculosis When Drug Susceptible and Drug Resistant Strains of M. Tuberculosis Are Detected

Specific Features of the Immune Response to Tuberculosis When Drug Susceptible and Drug Resistant Strains of M. Tuberculosis Are Detected

Modification of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant in the surgical treatment of widespread destructive pulmonary tuberculosis

Modification of transsternal occlusion of the main bronchus by plastic surgery of the anterior mediastinum with a mesh implant in the surgical treatment of widespread destructive pulmonary tuberculosis

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